Organelle-targeted photosensitizers for precision photodynamic therapy
Subcellular organelles are the cornerstones of cells, and destroying them will cause cell
dysfunction and even death. Therefore, realizing precise organelle targeting of …
dysfunction and even death. Therefore, realizing precise organelle targeting of …
Mitochondria-targeted triphenylphosphonium-based compounds: syntheses, mechanisms of action, and therapeutic and diagnostic applications
Mitochondria are recognized as one of the most important targets for new drug design in
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …
[HTML][HTML] Two-photon AIE bio-probe with large Stokes shift for specific imaging of lipid droplets
Lipid droplets are dynamic organelles involved in various physiological processes and their
detection is thus of high importance to biomedical research. Recent reports show that AIE …
detection is thus of high importance to biomedical research. Recent reports show that AIE …
Fluorescent probes for the visualization of cell viability
Conspectus Monitoring cell viability is a crucial task essential for the fundamental studies in
apoptosis, necrosis, and drug discovery. Cell apoptosis and necrosis are significant to …
apoptosis, necrosis, and drug discovery. Cell apoptosis and necrosis are significant to …
Molecular photosensitisers for two-photon photodynamic therapy
Two-photon excitation has attracted the attention of biologists, especially after the
development of two-photon excited microscopy in the nineties. Since then, new applications …
development of two-photon excited microscopy in the nineties. Since then, new applications …
Ligand design to acquire specificity to intended G‐quadruplex structures
S Asamitsu, T Bando… - Chemistry–A European …, 2019 - Wiley Online Library
AG‐quadruplex is a nucleic acid secondary structure that is adopted by guanine‐rich
sequences, and is considered to be relevant in various pharmacological and biological …
sequences, and is considered to be relevant in various pharmacological and biological …
A dual‐functional photosensitizer for ultraefficient photodynamic therapy and synchronous anticancer efficacy monitoring
Y Gao, X Wang, X He, Z He, X Yang… - Advanced Functional …, 2019 - Wiley Online Library
A dual‐functional photosensitizer that demonstrates exceptional photodynamic therapy
(PDT) efficacy while simultaneously self‐monitoring the therapeutic response in real time is …
(PDT) efficacy while simultaneously self‐monitoring the therapeutic response in real time is …
Mitochondrial imaging with combined fluorescence and stimulated Raman scattering microscopy using a probe of the aggregation-induced emission characteristic
In vivo quantitative measurement of biodistribution plays a critical role in the drug/probe
development and diagnosis/treatment process monitoring. In this work, we report a probe …
development and diagnosis/treatment process monitoring. In this work, we report a probe …
Two-photon excitation photosensitizers for photodynamic therapy: From small-molecules to nano-complex systems
Two-photon excitation photodynamic therapy (TP-PDT), which uses near-infrared light (>
700 nm) as an excitation source, is an essential approach for modern deep-tissue …
700 nm) as an excitation source, is an essential approach for modern deep-tissue …
Mitochondria‐specific agents for photodynamic cancer therapy: a key determinant to boost the efficacy
X Li, Y Zhao, T Zhang, D Xing - Advanced Healthcare Materials, 2021 - Wiley Online Library
Mitochondria‐targeted photodynamic therapy (Mt‐PDT), which enables the photogenerated
cytotoxic oxygen species with fatal oxidative damage to block mitochondrial functions, has …
cytotoxic oxygen species with fatal oxidative damage to block mitochondrial functions, has …