Kratom (Mitragyna speciosa Korth., Rubiaceae) is a plant native to Southeast Asia, where it
has been used for centuries as a mild stimulant and as medicine for various ailments. More …

ABSTRACT Introduction Kratom (Mitragyna speciosa) has generated substantial clinical and
scientific interest as a complex natural product. Its predominant alkaloid mitragynine and …

Background: Kratom (Mitragyna speciosa) consumption and associated health effects have
raised debates in the United States. Although most people using this herb do not experience …

Abstract Introduction Kratom (Mitragyna speciosa) is a tropical plant traditionally used as an
ethnomedicinal remedy for several conditions in South East Asia. Despite the increased …

Abstract Purpose of Review This work aims to provide an up-to-date review of the preclinical
and clinical scientific literature on the therapeutic value of kratom to better understand the …

Abstract Used in Southeast Asia for generations, kratom gained popularity in the United
States and elsewhere over the past several decades. Derived from Mitragyna speciosa …

Background: Kratom or Mitragyna speciosa (Korth.) has received overwhelming attention
recently due to its alleged pain-relieving effects. Despite its potential therapeutic value …

Drugs are regulated in the United States (US) by the Controlled Substances Act (CSA) if
assessment of their abuse potential, including public health risks, show such control is …

Abstract Kratom (Mitragyna speciosa Korth.) is a tree native to Southeast Asia with dose-
dependent stimulant and opioid-like effects. Dried, powdered leaf material is among the …

Background Epidemic increases in opioid deaths prompted policies limiting access to
prescription opioids in North America. Consequently, the over-the-counter opioids …