Breast cancer treatments: updates and new challenges

A Burguin, C Diorio, F Durocher - Journal of personalized medicine, 2021 - mdpi.com
Breast cancer (BC) is the most frequent cancer diagnosed in women worldwide. This
heterogeneous disease can be classified into four molecular subtypes (luminal A, luminal B …

Breast cancer treatment: a review

AG Waks, EP Winer - Jama, 2019 - jamanetwork.com
Importance Breast cancer will be diagnosed in 12% of women in the United States over the
course of their lifetimes and more than 250 000 new cases of breast cancer were diagnosed …

PROLIDASE: A Review from Discovery to its Role in Health and Disease

I Eni-Aganga, ZM Lanaghan… - Frontiers in Molecular …, 2021 - frontiersin.org
Prolidase (peptidase D), encoded by the PEPD gene, is a ubiquitously expressed cytosolic
metalloproteinase, the only enzyme capable of cleaving imidodipeptides containing C …

Nanotechnology revolutionises breast cancer treatment: harnessing lipid-based nanocarriers to combat cancer cells

F Fatima Qizilbash, A Sartaj, Z Qamar… - Journal of Drug …, 2023 - Taylor & Francis
One of the most common cancers that occur in females is breast cancer. Despite the
significant leaps and bounds that have been made in treatment of breast cancer, the disease …

Rationally designed ruthenium complexes for breast cancer therapy

G Golbaghi, A Castonguay - Molecules, 2020 - mdpi.com
Since the discovery of the anticancer potential of ruthenium-based complexes, several
species were reported as promising candidates for the treatment of breast cancer, which …

Targeted co-delivery of daunorubicin and cytarabine based on the hyaluronic acid prodrug modified liposomes

GF Boafo, Y Shi, Q Xiao, KT Magar, M Zoulikha… - Chinese Chemical …, 2022 - Elsevier
Breast cancer is the most prevalent cancer in women, and it was hard to prevent or diagnose
at an early stage. Thus, it is imperative to develop advanced therapeutics for effective …

Potential roles and molecular mechanisms of bioactive ingredients in Curcumae Rhizoma against breast cancer

P Zhao, J Qiu, C Pan, Y Tang, M Chen, H Song, J Yang… - Phytomedicine, 2023 - Elsevier
Background Breast cancer is the most prevalent cancer worldwide, with high morbidity and
mortality. Despite great advances in the therapeutic strategies, the survival rate in the past …

Current perspectives and trends in nanoparticle drug delivery systems in breast cancer: bibliometric analysis and review

S Sun, Y Wang, X Gao, H Wang, L Zhang… - … in Bioengineering and …, 2023 - frontiersin.org
The treatment of breast cancer (BC) is a serious challenge due to its heterogeneous nature,
multidrug resistance (MDR), and limited therapeutic options. Nanoparticle-based drug …

KLF6 activates Sp1-mediated prolidase transcription during TGF-β1 signaling

I Eni-Aganga, ZM Lanaghan, F Ismail… - Journal of Biological …, 2024 - ASBMB
Prolidase (PEPD) is the only hydrolase that cleaves the dipeptides containing C-terminal
proline or hydroxyproline-the rate-limiting step in collagen biosynthesis. However, the …

Emerging immunotherapies against novel molecular targets in breast cancer

V Sivaganesh, N Promi, S Maher… - International Journal of …, 2021 - mdpi.com
Immunotherapy is a highly emerging form of breast cancer therapy that enables clinicians to
target cancers with specific receptor expression profiles. Two popular immunotherapeutic …