J Li, ML Kalev-Zylinska - Frontiers in genetics, 2022 - frontiersin.org
Myeloid leukemia associated with Down syndrome (ML-DS) has a unique molecular landscape that differs from other subtypes of acute myeloid leukemia. ML-DS is often …
Acute myeloid leukemia (AML) has a poor prognosis and a heterogeneous mutation landscape. Although common mutations are well-studied, little research has characterized …
NPM1 mutated acute myeloid leukemia (AML) comprises roughly 30% of all AML cases and is mainly classified as favorable or intermediate-risk according to the European Leukemia …
T Miyajima, M Onozawa, S Yoshida… - European Journal of …, 2023 - Wiley Online Library
Objectives The cryptic fusion oncogene NUP98:: NSD1 is known to be associated with FLT3‐ ITD mutation in acute myeloid leukemia (AML), and an independent poor prognostic factor in …
J Wu, H Yan, C Xiang - Hematology, 2023 - Taylor & Francis
ABSTRACT Wilms' tumor gene 1 (WT1) is a transcription and post-translational factor that has a crucial role in the biological and pathological processes of several human …
A Baranwal, R Basmaci, R He, D Viswanatha… - Blood …, 2024 - ashpublications.org
The Wilms tumor 1 (WT1) gene, located at locus 11p13, is a tumor suppressor gene that encodes a zinc-finger transcription factor. 1, 2 The presence of WT1 gene mutation (mWT1) …
Y Wang, D Huang, L Liu, A Wang… - … Methods in Medicine, 2022 - Wiley Online Library
Objective. To investigate the efficacy and safety of azacytidine and B‐cell lymphoma/leukemia‐2 inhibitors in the treatment of patients with acute myeloid leukemia …
Breast cancer accounts for around 25% of all newly-diagnosed cancers, and is one of the leading causes of cancer-related death in women due to a high rate of relapse and …