Therapeutic potential of ectopic olfactory and taste receptors

SJ Lee, I Depoortere, H Hatt - Nature Reviews Drug Discovery, 2019 - nature.com
Olfactory and taste receptors are expressed primarily in the nasal olfactory epithelium and
gustatory taste bud cells, where they transmit real-time sensory signals to the brain …

Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C (ut) annabinoid” System

KF Tóth, D Ádám, T Bíró, A Oláh - Molecules, 2019 - mdpi.com
The endocannabinoid system (ECS) has lately been proven to be an important, multifaceted
homeostatic regulator, which influences a wide-variety of physiological processes all over …

Cosmetic and therapeutic applications of fish oil's fatty acids on the skin

TH Huang, PW Wang, SC Yang, WL Chou, JY Fang - Marine drugs, 2018 - mdpi.com
Fish oil has been broadly reported as a potential supplement to ameliorate the severity of
some skin disorders such as photoaging, skin cancer, allergy, dermatitis, cutaneous …

GPR120/FFAR4 pharmacology: focus on agonists in type 2 diabetes mellitus drug discovery

G Carullo, S Mazzotta, M Vega-Holm… - Journal of Medicinal …, 2021 - ACS Publications
The G-protein coupled receptors (GPCRs) activated by free fatty acids (FFAs) have emerged
as new and exciting drug targets, due to their plausible translation from pharmacology to …

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M Mititelu, CN Oancea - 2017 - researchgate.net
An evaluation of the behavioral risk factors that contribute to the incidence and evolution of
cancer in oncology patients was conducted through a cross-sectional study using a …

Regeneration and repair of skin wounds: various strategies for treatment

F Rezaie, M Momeni-Moghaddam… - … journal of lower …, 2019 - journals.sagepub.com
Skin as a mechanical barrier between the inner and outer environment of our body protects
us against infection and electrolyte loss. This organ consists of 3 layers: the epidermis …

The enigma of bioactivity and toxicity of botanical oils for skin care

EM Moore, C Wagner, S Komarnytsky - Frontiers in pharmacology, 2020 - frontiersin.org
Botanical oils have a long history of traditional use and are routinely applied to skin care.
The focus of this review is to contrast the functionality of skin oils versus the differential …

FFA4/GPR120: pharmacology and therapeutic opportunities

G Milligan, E Alvarez-Curto, BD Hudson… - Trends in …, 2017 - cell.com
Free Fatty Acid receptor 4 (FFA4), also known as GPR120, is a G-protein-coupled receptor
(GPCR) responsive to long-chain fatty acids that is attracting considerable attention as a …

Endogenous lipid-GPR120 signaling modulates pancreatic islet homeostasis to different extents

YQ Du, XY Sha, J Cheng, J Wang, JY Lin, WT An… - Diabetes, 2022 - Am Diabetes Assoc
Long-chain fatty acids (LCFAs) are not only energy sources but also serve as signaling
molecules. GPR120, an LCFA receptor, plays key roles in maintaining metabolic …

Characterization of Some Dermato-Cosmetic Preparations with Marine Lipids from Black Sea Wild Stingray

M Mititelu, M Licu, CE Lupu, SM Neacșu, G Olteanu… - Marine Drugs, 2023 - mdpi.com
The traditional knowledge about the therapeutic and nutritional value of fish has been
unanimously recognized among the population since ancient times. So, thanks to the …