A draft genome of the medicinal plant Cremastra appendiculata (D. Don) provides insights into the colchicine biosynthetic pathway
J Wang, J Xie, H Chen, X Qiu, H Cui, Y Liu… - Communications …, 2022 - nature.com
Abstract Cremastra appendiculata (D. Don) Makino is a rare terrestrial orchid with a high
market value as an ornamental and Chinese traditional medicinal herb with a wide range of …
market value as an ornamental and Chinese traditional medicinal herb with a wide range of …
Bacillus subtilis BS-15 Effectively Improves Plantaricin Production and the Regulatory Biosynthesis in Lactiplantibacillus plantarum RX-8
G Liu, R Nie, Y Liu, X Li, J Duan, X Hao… - Frontiers in …, 2022 - frontiersin.org
Plantaricin is a broad-spectrum bacteriocin produced by Lactiplantibacillus plantarum with
significant food industry application potential. It was found that the plantaricin production of …
significant food industry application potential. It was found that the plantaricin production of …
Atomic-level understanding on conformational flexibility of neochlorogenic and chlorogenic acids and their inclusion complexation with β-cyclodextrin
T Aree - Food Hydrocolloids, 2023 - Elsevier
Neochlorogenic acid (NCA) and chlorogenic acid (CGA) are positional isomers, abundant in
plums and prunes. Their limited bioavailability due to instability under ambient conditions …
plums and prunes. Their limited bioavailability due to instability under ambient conditions …
Structural and biochemical analyses reveal that chlorogenic acid inhibits the shikimate pathway
Chlorogenic acid (CGA) is a phenolic compound with well-known antibacterial properties
against pathogens. In this study, structural and biochemical characterization was used to …
against pathogens. In this study, structural and biochemical characterization was used to …
Biophysical and in silico interaction studies of aporphine alkaloids with Malonyl-CoA: ACP transacylase (FabD) from drug resistant Moraxella catarrhalis
Malonyl-CoA: acyl carrier protein transacylase (FabD), being an essential enzyme of the
FAS II pathway, is an attractive target for developing broad-spectrum antibiotics. It performs …
FAS II pathway, is an attractive target for developing broad-spectrum antibiotics. It performs …
Domain cross-talk within a bifunctional enzyme provides catalytic and allosteric functionality in the biosynthesis of aromatic amino acids
Because of their special organization, multifunctional enzymes play crucial roles in
improving the performance of metabolic pathways. For example, the bacterium Prevotella …
improving the performance of metabolic pathways. For example, the bacterium Prevotella …
Biochemical and biophysical characterization of 1, 4-naphthoquinone as a dual inhibitor of two key enzymes of type II fatty acid biosynthesis from Moraxella catarrhalis
The fatty acid biosynthesis (FAS II) is a vital process in bacteria and regarded as an
attractive pathway for the development of potential antimicrobial agents. In this study, we …
attractive pathway for the development of potential antimicrobial agents. In this study, we …
Isolation and biochemical characterization of a metagenome-derived 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase gene from subtropical marine …
Deoxy-d-arabino-heptulosonate-7-phosphate synthase (DAHPS) is a key rate-limiting
enzyme in aromatic amino acid anabolism. A new I β-type DAHPS gene (aro1A) was …
enzyme in aromatic amino acid anabolism. A new I β-type DAHPS gene (aro1A) was …
Characterization of isoflavonoids as inhibitors of β-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Moraxella catarrhalis: Kinetics, spectroscopic …
Backgroud β-hydroxyacyl-acyl carrier protein dehydratase (FabZ) is an essential component
of type II fatty acid biosynthesis (FAS II) pathway in bacteria. It performs dehydration of β …
of type II fatty acid biosynthesis (FAS II) pathway in bacteria. It performs dehydration of β …
In vitro metal catalyzed oxidative stress in DAH7PS: methionine modification leads to structure destabilization and induce amorphous aggregation
The first committed step of the shikimate pathway is catalyzed by a metalloenzyme 3-deoxy-
d-arabino-heptulosonate-7-phosphate synthase (DAH7PS), which exhibits vulnerability to …
d-arabino-heptulosonate-7-phosphate synthase (DAH7PS), which exhibits vulnerability to …