[HTML][HTML] Multispherical shapes of vesicles highlight the curvature elasticity of biomembranes

R Lipowsky - Advances in Colloid and Interface Science, 2022 - Elsevier
Giant lipid vesicles form unusual multispherical or “multi-balloon” shapes consisting of
several spheres that are connected by membrane necks. Such multispherical shapes have …

Polymyxin B-Enriched Exogenous Lung Surfactant: Thermodynamics and Structure

N Královič-Kanjaková, A Asi Shirazi, L Hubčík… - Langmuir, 2024 - ACS Publications
The use of an exogenous pulmonary surfactant (EPS) to deliver other relevant drugs to the
lungs is a promising strategy for combined therapy. We evaluated the interaction of …

Self-limiting multimerization of α-synuclein on membrane and its implication in Parkinson's diseases

DF Ma, S Zhang, SY Xu, Z Huang, Y Tao, F Chen… - Science …, 2024 - science.org
α-Synuclein (α-syn), a crucial molecule in Parkinson's disease (PD), is known for its
interaction with lipid membranes, which facilitates vesicle trafficking and modulates its …

Interactions of bacterial quorum sensing signals with model lipid membranes: influence of membrane composition on membrane remodeling

CG Gahan, RC Van Lehn, HE Blackwell, DM Lynn - Langmuir, 2022 - ACS Publications
We report the influence of membrane composition on the multiscale remodeling of
multicomponent lipid bilayers initiated by contact with the amphiphilic bacterial quorum …

The Possibilities of Studying Biological Objects on a Pulsed Reactor

AV Vlasov, YL Ryzhykau, IV Manukhov, SV Bazhenov… - Biophysics, 2023 - Springer
Small-angle scattering makes it possible to solve structural biology problems without special
sample preparation, which is typical for such methods as X-ray diffraction on protein crystals …

Cations Do Not Alter the Membrane Structure of POPC—A Lipid With an Intermediate Area

S Kurakin, O Ivankov, V Skoi, A Kuklin… - Frontiers in Molecular …, 2022 - frontiersin.org
Combining small-angle neutron scattering (SANS), small-angle X-ray scattering (SAXS), and
densitometric measurements, we have studied the interactions of the divalent cations Ca2+ …

Thermodynamic Driving Forces for Divalent Cations Binding to Zwitterionic Phospholipid Membranes

Y Dong, L Fu, J Song, S Zhang, X Li… - The Journal of …, 2022 - ACS Publications
We calculated the free energies for calcium, magnesium, and zinc ions binding to a
zwitterionic phospholipid bilayer by using molecular dynamics simulations and the …

Osmotic Pressure Enables High-Yield Assembly of Giant Vesicles in Solutions of Physiological Ionic Strengths

A Cooper, V Girish, AB Subramaniam - Langmuir, 2023 - ACS Publications
Giant unilamellar vesicles (GUVs) are micrometer-scale minimal cellular mimics that are
useful for bottom-up synthetic biology and drug delivery. Unlike assembly in low-salt …

Effect of Divalent Cations on Polarity and Hydration at the Lipid/Water Interface Probed by 4-Aminophthalimide-Based Dyes

P Alam, P Kumar, H Sahu, D Sardana… - The Journal of …, 2025 - ACS Publications
The ion binding to the lipid/water interface can substantially influence the structural,
functional, and dynamic properties of the cell membrane. Despite extensive research on ion …

Lipid headgroup and side chain architecture determine manganese-induced dose dependent membrane rigidification and liposome size increase

K Sule, EJ Prenner - European Biophysics Journal, 2022 - Springer
Metal ion-membrane interactions have gained appreciable attention over the years resulting
in increasing investigations into the mode of action of toxic and essential metals. More work …