Cell-type-specific tools facilitate the identification and functional characterization of the
distinct cell types that form the complexity of neuronal circuits. A large collection of existing …

Drosophila melanogaster has been used as a model system to identify and characterize
genetic contributions to development, homeostasis, and to investigate the molecular …

Techniques that enable precise manipulations of subsets of neurons in the fly central
nervous system have greatly facilitated our understanding of the neural basis of behavior …

Alcohol tolerance is a neuroadaptive response that leads to a reduction in the effects of
alcohol caused by previous exposure. Tolerance plays a critical role in the development of …

The ability to independently control gene expression in two different tissues in the same
animal is emerging as a major need, especially in the context of inter-organ communication …

The Trojan exon method, which makes use of intronically inserted T2A-Gal4 cassettes, has
been widely used in Drosophila to create thousands of gene-specific Gal4 driver lines …

Most multicellular organisms consist of tremendous diversity of cells. Genetic drivers that
target specific groups of cells have played a key role in dissecting complex biological …

Temperature is an important control factor for biologics biomanufacturing in precision
fermentation. Here, we explored a highly responsive low temperature-inducible genetic …

Communication between cells in metazoan organisms is mediated by a remarkably small
number of highly conserved signaling pathways. Given this small number of signaling …

Split inteins are biological mechanisms for the operation of the spatiotemporal control of
protein activities. They function through protein trans-splicing, in which their N-and C …