First report on molecular docking analysis and drug resistance substitutions to approved HCV NS5A and NS5B inhibitors amongst Iranian patients
Z Hasanshahi, A Hashempour, F Ghasabi… - Bmc …, 2021 - Springer
Abstract Background NS5A and NS5B proteins of hepatitis C virus (HCV) are the main
targets of compounds that directly inhibit HCV infections. However, the emergence of …
targets of compounds that directly inhibit HCV infections. However, the emergence of …
Identification of NS5B resistance against SOFOSBUVIR in hepatitis C virus genotype 3a, naive and treated patients
Aims Pakistan has the second highest prevalence of HCV with genotype 3a (GT‐3a) being
the most frequently circulating genotype. Currently, resistance‐associated substitutions …
the most frequently circulating genotype. Currently, resistance‐associated substitutions …
Distribution of Primary Resistance Mutations in Saint Petersburg in Patients with Chronic Hepatitis C
D Valutite, Y Ostankova, A Semenov, L Lyalina… - Diagnostics, 2022 - mdpi.com
The advent of direct-acting antiviral drugs (DAAs) was a breakthrough in the treatment of
patients with chronic hepatitis C, yet high viral replication errors can lead to the development …
patients with chronic hepatitis C, yet high viral replication errors can lead to the development …
Resistance mutations of NS3 and NS5b in treatment-naïve patients infected with hepatitis C virus in Santa Catarina and Rio Grande do Sul states, Brazil
E Andrade, D Rocha, M Fontana-Maurell… - … and Molecular Biology, 2020 - SciELO Brasil
Hepatitis C virus (HCV) infection is a worldwide health problem. Nowadays, direct-acting
antiviral agents (DAAs) are the main treatment for HCV; however, the high level of virus …
antiviral agents (DAAs) are the main treatment for HCV; however, the high level of virus …
Molecular characterization of hepatitis C virus for developed antiviral agents resistance mutations and new insights into in-silico prediction studies
Background Identification and characterization of developed antiviral drug resistance
mutations are key to the success of antiviral therapies against hepatitis C virus (HCV), which …
mutations are key to the success of antiviral therapies against hepatitis C virus (HCV), which …
[PDF][PDF] Consensus recommendations on the diagnosis and treatment of hepatitis c virus infection in sub Saharan Africa
E Gane, M Charlton, C Onyekwere, AK Emile… - Gastroenterol …, 2019 - researchgate.net
Abstract Sub-Saharan Africa has a high burden of hepatitis C virus (HCV) infection.
Therefore, 10 experts from Africa convened, reviewed the literature, and provided …
Therefore, 10 experts from Africa convened, reviewed the literature, and provided …