The Role of non-coding RNAs in colorectal cancer, with a focus on its autophagy

L Chen, M He, M Zhang, Q Sun, S Zeng, H Zhao… - Pharmacology & …, 2021 - Elsevier
Colorectal cancer (CRC) is one of malignant afflictions burdening people worldwide, mainly
caused by shortages of effective medical intervention and poorly mechanistic understanding …

Targeting gastric cancer stem cells to enhance treatment response

X Rao, C Zhang, H Luo, J Zhang, Z Zhuang, Z Liang… - Cells, 2022 - mdpi.com
Gastric cancer (GC) was the fourth deadliest cancer in the world in 2020, and about 770,000
people died from GC that year. The death of patients with GC is mainly caused by the …

Implications of photodynamic cancer therapy: An overview of PDT mechanisms basically and practically

N Sobhani, AA Samadani - Journal of the Egyptian National Cancer …, 2021 - Springer
Background Tumor eradication is one of the most important challengeable categories in
oncological studies. In this account, besides the molecular genetics methods including cell …

Adenovirus biology, recombinant adenovirus, and adenovirus usage in gene therapy

M Watanabe, Y Nishikawaji, H Kawakami, K Kosai - Viruses, 2021 - mdpi.com
Gene therapy is currently in the public spotlight. Several gene therapy products, including
oncolytic virus (OV), which predominantly replicates in and kills cancer cells, and COVID-19 …

Unmasking the deceptive nature of cancer stem cells: The role of cd133 in revealing their secrets

J Pospieszna, H Dams-Kozlowska, W Udomsak… - International Journal of …, 2023 - mdpi.com
Cancer remains a leading cause of death globally, and its complexity poses a significant
challenge to effective treatment. Cancer stem cells and their markers have become key …

The roles of noncoding RNAs in the development of osteosarcoma stem cells and potential therapeutic targets

J Liu, G Shang - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Osteosarcoma (OS) is the common bone tumor in children and adolescents. Because of
chemotherapy resistance, the OS patients have a poor prognosis. The one reason of …

CDKN2B-AS1 as a novel therapeutic target in cancer: Mechanism and clinical perspective

A Hjazi, E Ghaffar, W Asghar, HA Khalaf… - Biochemical …, 2023 - Elsevier
Long non-coding RNAs (lncRNA) have been identified as essential components having
considerable modulatory impacts on biological activities through altering gene transcription …

The biology of SCUBE

YC Lin, BK Sahoo, SS Gau, RB Yang - Journal of biomedical science, 2023 - Springer
Abstract The SCUBE [Signal peptide-Complement C1r/C1s, Uegf, Bmp1 (CUB)-Epithelial
growth factor domain-containing protein] family consists of three proteins in vertebrates …

Cancer stem cells targets and combined therapies to prevent cancer recurrence

PK Raghav, Z Mann - Life Sciences, 2021 - Elsevier
Cancer stem cells (CSCs) control the dynamics of tumorigenesis by self-renewal ability and
differentiation potential. These properties contribute towards tumor malignancy, metastasis …

[HTML][HTML] From Crypts to Cancer: A Holistic Perspective on Colorectal Carcinogenesis and Therapeutic Strategies

E Gharib, GA Robichaud - International journal of molecular sciences, 2024 - mdpi.com
Colorectal cancer (CRC) represents a significant global health burden, with high incidence
and mortality rates worldwide. Recent progress in research highlights the distinct clinical …