In the past decades, adequate and well-planned management of chronic wounds has
reached an elevated importance to improve human's quality of life and extend life …

Background Indications for the use of negative pressure wound therapy (NPWT) are broad
and include prophylaxis for surgical site infections (SSIs). Existing evidence for the …

Delayed wound healing can cause significant issues for immobile and ageing individuals as
well as those living with co-morbid conditions such as diabetes, cardiovascular disease, and …

1. Introduction Since its introduction in clinical practice in the early 1990's negative pressure
wounds therapy (NPWT) has become widely used in the management of complex wounds in …

Importance Surgical site infections (SSIs) are common after laparotomy wounds and are
associated with a significant economic burden. The use of negative pressure wound therapy …

Mediastinitis continues to be an important and life-threatening complication after median
sternotomy despite advances in prevention and treatment strategies, with an incidence of …

Background Foot wounds in people with diabetes mellitus (DM) are a common and serious
global health issue. People with DM are prone to developing foot ulcers and, if these do not …

Importance Following surgery to treat major trauma–related fractures, deep wound infection
rates are high. It is not known if negative pressure wound therapy can reduce infection rates …

Significance: Almost 7 million Americans have chronic cutaneous wounds and billions of
dollars are spent on their treatment. The number of patients with nonhealing wounds keeps …

Background Traumatic wounds (wounds caused by injury) range from abrasions and minor
skin incisions or tears, to wounds with extensive tissue damage or loss as well as damage to …