Advanced biomaterials for repairing and reconstruction of mandibular defects

Q Zhang, W Wu, C Qian, W Xiao, H Zhu, J Guo… - Materials Science and …, 2019 - Elsevier
Mandibles are the largest and strongest bone in the human face and are often severely
compromised by mandibular defects, compromising the quality of life of patients. Mandibular …

Application of fibrin associated with photobiomodulation as a promising strategy to improve regeneration in tissue engineering: A systematic review

CHB Reis, DV Buchaim, AC Ortiz, SOM Fideles… - Polymers, 2022 - mdpi.com
Fibrin, derived from proteins involved in blood clotting (fibrinogen and thrombin), is a
biopolymer with different applications in the health area since it has hemostasis …

[HTML][HTML] Encapsulation of lyophilized platelet-rich fibrin in alginate-hyaluronic acid hydrogel as a novel vascularized substitution for myocardial infarction

B Qian, Q Yang, M Wang, S Huang, C Jiang, H Shi… - Bioactive materials, 2022 - Elsevier
Cardiovascular diseases such as myocardial infarction (MI) are among the major causes of
death worldwide. Although intramyocardial injection of hydrogels can effectively enhance …

Evolution and clinical advances of platelet-rich fibrin in musculoskeletal regeneration

R Narayanaswamy, BP Patro, N Jeyaraman… - Bioengineering, 2023 - mdpi.com
Over the past few decades, various forms of platelet concentrates have evolved with
significant clinical utility. The newer generation products, including leukocyte-platelet-rich …

Freeze-drying of platelet-rich plasma: the quest for standardization

I Andia, A Perez-Valle, C Del Amo… - International journal of …, 2020 - mdpi.com
The complex biology of platelets and their involvement in tissue repair and inflammation
have inspired the development of platelet-rich plasma (PRP) therapies for a broad array of …

Novel applications of platelet concentrates in tissue regeneration

ZY Ding, Y Tan, Q Peng, J Zuo… - Experimental and …, 2021 - spandidos-publications.com
Numerous studies have explored the suitability of biocompatible materials in regenerative
medicine. Platelet concentrates are derived from centrifuged blood and are named …

Effects of platelet-rich fibrin produced by three centrifugation protocols on bone neoformation in defects created in rat calvaria

DS Ferreira Sávio, LMP Silva, GGD Reis, RJ Denardi… - Platelets, 2023 - Taylor & Francis
This study evaluated the potential of Leukocyte-platelet-rich fibrin (L-PRF; fixed angle
centrifugation protocol), Advanced-platelet-rich fibrin (A-PRF; low-speed fixed angle …

The effects of platelet-rich fibrin in the behavior of mineralizing cells related to bone tissue regeneration—a scoping review of in vitro evidence

R de Lima Barbosa, E Stellet Lourenço… - Journal of Functional …, 2023 - mdpi.com
Platelet-rich fibrin (PRF) is a second-generation blood concentrate that serves as an
autologous approach for both soft and hard tissue regeneration. It provides a scaffold for cell …

Biological and mechanical properties of platelet-rich fibrin membranes after thermal manipulation and preparation in a single-syringe closed system

D Kardos, I Hornyák, M Simon, A Hinsenkamp… - International journal of …, 2018 - mdpi.com
Platelet-rich fibrin (PRF) membrane is a three-dimensional biodegradable biopolymer,
which consists of platelet derived growth factors enhancing cell adhesion and proliferation. It …

Standardization of animal models and techniques for platelet-rich fibrin production: a narrative review and guideline

CF Mourão, A Lowenstein, RC Mello-Machado… - Bioengineering, 2023 - mdpi.com
Experimental research is critical for advancing medical knowledge and enhancing patient
outcomes, including in vitro and in vivo preclinical assessments. Platelet-rich fibrin (PRF) is …