[HTML][HTML] Unveiling the cellular landscape: insights from single-cell RNA sequencing in multiple myeloma

X Li, Z Lin, F Zhao, T Huang, W Fan, L Cen… - Frontiers in …, 2024 - frontiersin.org
Objective The aim of this research was to gain a thorough understanding of the processes
involved in cell communication and discover potential indicators for treating multiple …

Examining the evidence for mutual modulation between m6A modification and circular RNAs: current knowledge and future prospects

X Tang, M Guo, Y Zhang, J Lv, C Gu, Y Yang - Journal of Experimental & …, 2024 - Springer
The resistance of cancer cells to treatment significantly impedes the success of therapy,
leading to the recurrence of various types of cancers. Understanding the specific …

Characterizing mitochondrial features in osteoarthritis through integrative multi-omics and machine learning analysis

Y Wu, H Hu, T Wang, W Guo, S Zhao… - Frontiers in immunology, 2024 - frontiersin.org
Purpose Osteoarthritis (OA) stands as the most prevalent joint disorder. Mitochondrial
dysfunction has been linked to the pathogenesis of OA. The main goal of this study is to …

[HTML][HTML] CDCA8, a mitosis-related gene, as a prospective pan-cancer biomarker: implications for survival prognosis and oncogenic immunology

H Hu, M Umair, SA Khan, AI Sani, S Iqbal… - American Journal of …, 2024 - ncbi.nlm.nih.gov
Background: Human cell division cycle-associated protein 8 (CDCA8), a critical regulator of
mitosis, has been identified as a prospective prognostic biomarker in several cancer types …

[HTML][HTML] Comprehensive analysis of disulfidptosis-related genes: a prognosis model construction and tumor microenvironment characterization in clear cell renal cell …

B Yi, X Wei, D Liu, L Jing, S Xu, M Zhang… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Background: Disulfidptosis, a form of cell death induced by abnormal intracellular
accumulation of disulfides, is a newly recognized variety of cell death. Clear cell renal cell …

Exploring the molecular landscape of osteosarcoma through PTTG family genes using a detailed multi-level methodology

Y Lu, D Wang, G Chen, Z Shan, D Li - Frontiers in Genetics, 2024 - frontiersin.org
Background Osteosarcoma (OS) poses a significant clinical challenge, necessitating a
comprehensive exploration of its molecular underpinnings. Methods This study explored the …

Comprehending the cuproptosis and cancer-immunity cycle network: delving into the immune landscape and its predictive role in breast cancer immunotherapy …

X Liu, F Xu, K Zhao, Y Liu, G Ye, X Zhang… - Frontiers in …, 2024 - frontiersin.org
Background The role of cuproptosis, a phenomenon associated with tumor metabolism and
immunological identification, remains underexplored, particularly in relation to the cancer …

Identification and validation of key genes in gastric cancer: insights from in silico analysis, clinical samples, and functional assays

X Pei, Y Luo, H Zeng, M Jamil, X Liu… - Aging (Albany NY …, 2024 - pmc.ncbi.nlm.nih.gov
Introduction: The underlying mechanisms of gastric cancer (GC) remain unknown.
Therefore, in this study, we employed a comprehensive approach, combining computational …

[HTML][HTML] Unveiling the unexplored novel signatures for osteoporosis via a detailed bioinformatics and molecular experiments based approach

H Zhou, Y Gul, Y Hameed, M Alhomrani… - American Journal of …, 2024 - ncbi.nlm.nih.gov
Unveiling the unexplored novel signatures for osteoporosis via a detailed bioinformatics and
molecular experiments based approach - PMC Back to Top Skip to main content NIH NLM Logo …

[HTML][HTML] Pan-cancer analysis of HS6ST2: associations with prognosis, tumor immunity, and drug resistance

L Huang, S Irshad, U Sultana, S Ali… - American Journal of …, 2024 - ncbi.nlm.nih.gov
Objectives: In this comprehensive study spanning 33 malignancies, we explored the
differential expression and prognostic significance of Heparan sulfate 6-O-sulfotransferase 2 …