The Green ChemisTREE: 20 years after taking root with the 12 principles

HC Erythropel, JB Zimmerman, TM de Winter… - Green chemistry, 2018 - pubs.rsc.org
The field of Green Chemistry has seen many scientific discoveries and inventions during the
20 years since the 12 Principles were first published. Inspired by tree diagrams that illustrate …

GreenMedChem: the challenge in the next decade toward eco-friendly compounds and processes in drug design

C Castiello, P Junghanns, A Mergel, C Jacob… - Green …, 2023 - pubs.rsc.org
Green chemistry has become a hot topic and the focus of not only many companies but also
researchers. Green chemistry strives to identify alternative and environmentally friendly …

Converting spent lithium cobalt oxide battery cathode materials into high-value products via a mechanochemical extraction and thermal reduction route

M Wang, Q Tan, Q Huang, L Liu, JF Chiang… - Journal of Hazardous …, 2021 - Elsevier
This study innovatively combines mechanochemistry and high-temperature thermal
reduction to achieve the recovery of valuable metals from spent LIBs. First, under the action …

Toward Property-Based Regulation

TD Muellers, PV Petrovic, JB Zimmerman… - Environmental …, 2023 - ACS Publications
An expanding web of adverse impacts on people and the environment has been steadily
linked to anthropogenic chemicals and their proliferation. Central to this web are the …

Application of the hard and soft, acids and bases (HSAB) theory as a method to predict cumulative neurotoxicity

F Melnikov, BC Geohagen, T Gavin, RM LoPachin… - Neurotoxicology, 2020 - Elsevier
Xenobiotic electrophiles can form covalent adducts that may impair protein function, damage
DNA, and may lead a range of adverse effects. Cumulative neurotoxicity is one adverse …

Current status and future challenges in molecular design for reduced hazard

P Coish, BW Brooks, EP Gallagher, TJ Kavanagh… - 2016 - ACS Publications
Synthetic chemicals and materials are the basis of our society and our economy. Yet, in spite
of all the advances in toxicology that have helped us understand and even predict toxicity …

The molecular design research network

P Coish, BW Brooks, EP Gallagher, M Mills… - Toxicological …, 2018 - academic.oup.com
Herein, we provide an overview of a research network that is aimed at fostering
interdisciplinary collaboration between chemists and toxicologists with the goal of rationally …

The Need for, and the Role of the Toxicological Chemist in the Design of Safer Chemicals

SC DeVito - Toxicological Sciences, 2018 - academic.oup.com
During the past several decades, there has been an ever increasing emphasis for designers
of new commercial (nonpharmaceutical) chemicals to include considerations of the potential …

Coupled molecular design diagrams to guide safer chemical design with reduced likelihood of perturbing the NRF2-ARE antioxidant pathway and inducing cytotoxicity

LQ Shen, F Melnikov, J Roethle, A Gudibanda… - Green …, 2016 - pubs.rsc.org
The NRF2-ARE antioxidant pathway is an important biological sensing and regulating
system that responds to xenochemicals. NRF2 senses chemically-caused production of …

[图书][B] Predictive Analytics for Toxicology: Applications in Discovery Science

LG Valerio Jr - 2024 - books.google.com
Predictive data science is already in use in many fields, but its application in toxicology is
new and sought after by non-animal alternative testing initiatives. Predictive Analytics for …