Many neurological disorders are characterised by structural changes in neuronal
connections, ranging from presymptomatic synaptic changes to the loss or rewiring of entire …

Gonadotropin releasing hormone (GnRH) neurons are hypothalamic neuroendocrine cells
that control sexual reproduction. During embryonic development, GnRH neurons migrate …

Makorin ring finger protein 3 (MKRN3) was identified as an inhibitor of puberty initiation with
the report of loss-of-function mutations in association with central precocious puberty …

Roundabout receptors are known to mediate Slit‐dependent repulsive signaling. However
in vertebrates, mounting evidence suggest that Robo3 is an unconventional Robo receptor …

ABSTRACT Gonadotropin-releasing hormone-1 (GnRH-1) neurons (GnRH-1 ns) migrate
from the developing olfactory pit into the hypothalamus during embryonic development …

Ulcerative colitis (UC) is a recurrent intestinal inflammatory disease. Slit2, a secreted protein,
interacts with its receptor Robo1 to regulate the differentiation of intestinal stem cells and …

The vomeronasal organ (VNO) is sensory organ located in the ventral region of the nasal
cavity in rodents. The VNO develops from the olfactory placode during the secondary …

Introduction: Idiopathic hypogonadotropic hypogonadism (IHH) is a rare reproductive
disorder resulting from gonadotropin-releasing hormone (GnRH) deficiency. However, in …

Motor neurons differentiate from a ventral column of progenitors and settle in static clusters,
the motor nuclei, next to the floor plate. Within these cell clusters, motor neurons receive …

Early-life deficiency of the serotonin transporter (SERT) gives rise to a wide range of
psychiatric-relevant phenotypes; however, the molecular and cellular targets of serotonin …