Marine natural products

JW Blunt, BR Copp, RA Keyzers, MHG Munro… - Natural product …, 2017 - pubs.rsc.org
Covering: 2015. Previous review: Nat. Prod. Rep., 2016, 33, 382–431 This review covers the
literature published in 2015 for marine natural products (MNPs), with 1220 citations (792 for …

[PDF][PDF] Natural product reports

JW Blunt, BR Copp, RA Keyzers, MH Munroa… - Nat Prod Rep, 2016 - academia.edu
This review covers the literature published in 2015 for marine natural products (MNPs), with
1220 citations (792 for the period January to December 2015) referring to compounds …

Harnessing ortho-Quinone Methides in Natural Product Biosynthesis and Biocatalysis

TN Purdy, BS Moore, AL Lukowski - Journal of natural products, 2022 - ACS Publications
The implementation of ortho-quinone methide (o-QM) intermediates in complex molecule
assembly represents a remarkably efficient strategy designed by Nature and utilized by …

Recent progress in the isolation, bioactivity, biosynthesis, and total synthesis of natural spiroketals

FM Zhang, SY Zhang, YQ Tu - Natural product reports, 2018 - pubs.rsc.org
Covering: 2011 to July 2017. Spiroketal (spiroacetal), a common moiety in numerous natural
products, drugs and functional molecules, has been a central topic in organic chemistry for a …

Ag/Brønsted acid co-catalyzed spiroketalization of β-alkynyl ketones toward spiro [chromane-2, 1′-isochromene] derivatives

S Liu, XC Lan, K Chen, WJ Hao, G Li, SJ Tu… - Organic …, 2017 - ACS Publications
A new Ag/Brønsted acid co-catalyzed spiroketalization of β-alkynyl ketones with para-
quinone methides (p-QMs) has been established, enabling multiple C–C and C–O bond …

Stereoselective reactions of ortho-quinone methide and ortho-quinone methide imines and their utility in natural product synthesis

CDT Nielsen, H Abas, AC Spivey - Synthesis, 2018 - thieme-connect.com
Herein presented is a review of the reactivity and synthetic utility of ortho-quinone methides
and ortho-quinone methide imines. These versatile intermediates have received significant …

Chemoenzymatic o-Quinone Methide Formation

TJ Doyon, JC Perkins, SA Baker Dockrey… - Journal of the …, 2019 - ACS Publications
Generation of reactive intermediates and interception of these fleeting species under
physiological conditions is a common strategy employed by Nature to build molecular …

Peniphenone and Penilactone Formation in Penicillium crustosum via 1,4-Michael Additions of ortho-Quinone Methide from Hydroxyclavatol to γ-Butyrolactones from …

J Fan, G Liao, F Kindinger… - Journal of the …, 2019 - ACS Publications
Penilactones A and B consist of a γ-butyrolactone and two clavatol moieties. We identified
two separate gene clusters for the biosynthesis of these key building blocks in Penicillium …

Rhodium-Catalyzed Difunctionalization of Alkenes Using Cyclic 1, 3-Dicarbonyl-Derived Iodonium Ylides

Z Zhang, B Su, J Gong, H Tao, S Mai - Organic Letters, 2024 - ACS Publications
Herein, we introduce an iodonium ylide strategy to achieve novel α-alkylation of cyclic 1, 3-
dicarbonyls through harnessing C (sp3)–Rh species generated from 5-exo-trig cyclization to …

Benzannulated spiroketal natural products: isolation, biological activity, biosynthesis, and total synthesis

RM Gillard, MA Brimble - Organic & Biomolecular Chemistry, 2019 - pubs.rsc.org
The spiroketal moiety is an important privileged scaffold that occurs extensively in natural
products, drugs, and bioactive molecules. Naturally occurring spiroketals are numerous …