The perfect storm: COVID-19 health disparities in US Blacks
N Phillips, IW Park, JR Robinson, HP Jones - Journal of racial and ethnic …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) accounts for over 180,000 deaths in the
USA. Although COVID-19 affects all racial ethnicities, non-Hispanic Blacks have the highest …
USA. Although COVID-19 affects all racial ethnicities, non-Hispanic Blacks have the highest …
Ellagic acid a multi-target bioactive compound for drug discovery in CNS? A narrative review
It is well-known that the health properties attributed to several fruits, herbs, seeds and their
processed foods/beverages are due to an important group of natural polyphenols classified …
processed foods/beverages are due to an important group of natural polyphenols classified …
Adventitial cell atlas of wt (wild type) and ApoE (apolipoprotein E)-deficient mice defined by single-cell RNA sequencing
Objective—Vascular adventitia encompasses progenitors and is getting recognized as the
major site of inflammation in early stage of atherosclerosis. However, the cellular atlas of the …
major site of inflammation in early stage of atherosclerosis. However, the cellular atlas of the …
Contribution of impaired parasympathetic activity to right ventricular dysfunction and pulmonary vascular remodeling in pulmonary arterial hypertension
D da Silva Gonçalves Bós, CEE Van Der Bruggen… - Circulation, 2018 - Am Heart Assoc
Background: The beneficial effects of parasympathetic stimulation have been reported in left
heart failure, but whether it would be beneficial for pulmonary arterial hypertension (PAH) …
heart failure, but whether it would be beneficial for pulmonary arterial hypertension (PAH) …
Cholinergic control of inflammation, metabolic dysfunction, and cognitive impairment in obesity-associated disorders: mechanisms and novel therapeutic opportunities
Obesity and obesity-associated disorders have become world-wide epidemics, substantially
increasing the risk of debilitating morbidity and mortality. A characteristic feature of these …
increasing the risk of debilitating morbidity and mortality. A characteristic feature of these …
Forebrain cholinergic dysfunction and systemic and brain inflammation in murine sepsis survivors
N Zaghloul, ME Addorisio, HA Silverman… - Frontiers in …, 2017 - frontiersin.org
Sepsis, a complex disorder characterized by immune, metabolic, and neurological
dysregulation, is the number one killer in the intensive care unit. Mortality remains …
dysregulation, is the number one killer in the intensive care unit. Mortality remains …
Hypertension, blood pressure variability, and target organ lesion
MC Irigoyen, K De Angelis, F Dos Santos… - Current hypertension …, 2016 - Springer
Hypertensive patients have a higher risk of developing health complications, particularly
cardiovascular (CV) events, than individuals with normal blood pressure (BP). Severity of …
cardiovascular (CV) events, than individuals with normal blood pressure (BP). Severity of …
[HTML][HTML] Neuroimmune nexus in the pathophysiology and therapy of inflammatory disorders: Role of α7 nicotinic acetylcholine receptors
KR Keever, VP Yakubenko, DB Hoover - Pharmacological Research, 2023 - Elsevier
The α7-nicotinic acetylcholine receptor (α7nAChR) is a key protein in the cholinergic anti-
inflammatory pathway (CAP) that links the nervous and immune systems. Initially, the …
inflammatory pathway (CAP) that links the nervous and immune systems. Initially, the …
Treating disorders across the lifespan by modulating cholinergic signaling with galantamine
Advances in understanding the regulatory functions of the nervous system have revealed
neural cholinergic signaling as a key regulator of cytokine responses and inflammation …
neural cholinergic signaling as a key regulator of cytokine responses and inflammation …