Background: Despite an increasing body of research highlighting their efficacy to treat a
broad range of medical conditions, psychedelic drugs remain a controversial issue among …

Renewed interest in the use of psychedelics in the treatment of psychiatric disorders
warrants a better understanding of the neurobiological mechanisms underlying the effects of …

This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …

Objective: The authors provide an evidenced-based summary of the literature on the clinical
application of psychedelic drugs in psychiatric disorders. Methods: Searches of PubMed and …

New psychoactive substances (NPS) are a heterogeneous group of substances. They are
associated with a number of health and social harms on an individual and societal level …

Previous attempts to identify a unified theory of brain serotonin function have largely failed to
achieve consensus. In this present synthesis, we integrate previous perspectives with new …

Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Growing interest has been seen in using lysergic acid diethylamide (LSD) in psychiatric
research and therapy. However, no modern studies have evaluated subjective and …

Recent clinical trials show that psychedelics such as LSD and psilocybin can be given safely
in controlled conditions, and can cause lasting psychological benefits with one or two …

Psychoactive substances with chemical structures or pharmacological profiles that are
similar to traditional drugs of abuse continue to emerge on the recreational drug market …