The FICI paradigm: Correcting flaws in antimicrobial in vitro synergy screens at their inception
M Gómara, S Ramón-García - Biochemical pharmacology, 2019 - Elsevier
Antibiotics have become the corner stone of modern medicine. However, our society is
currently facing one of the greatest challenges of its time: the emergence of antimicrobial …
currently facing one of the greatest challenges of its time: the emergence of antimicrobial …
The role of fosfomycin for multidrug-resistant gram-negative infections
The role of fosfomycin for multidrug-resistant gram-negative... : Current Opinion in Infectious
Diseases The role of fosfomycin for multidrug-resistant gram-negative infections : Current …
Diseases The role of fosfomycin for multidrug-resistant gram-negative infections : Current …
Synergistic activity of colistin-containing combinations against colistin-resistant Enterobacteriaceae
T Brennan-Krohn, A Pironti, JE Kirby - Antimicrobial agents and …, 2018 - Am Soc Microbiol
Resistance to colistin, a polypeptide drug used as an agent of last resort for the treatment of
infections caused by multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram …
infections caused by multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram …
The inoculum effect in the era of multidrug resistance: minor differences in inoculum have dramatic effect on MIC determination
KP Smith, JE Kirby - Antimicrobial agents and chemotherapy, 2018 - Am Soc Microbiol
The observed MIC may depend on the number of bacteria initially inoculated into the assay.
This phenomenon is termed the inoculum effect (IE) and is often most pronounced for β …
This phenomenon is termed the inoculum effect (IE) and is often most pronounced for β …
Streptothricin F is a bactericidal antibiotic effective against highly drug-resistant gram-negative bacteria that interacts with the 30S subunit of the 70S ribosome
The streptothricin natural product mixture (also known as nourseothricin) was discovered in
the early 1940s, generating intense initial interest because of excellent gram-negative …
the early 1940s, generating intense initial interest because of excellent gram-negative …
Addressing COVID‐19 drug development with artificial intelligence
D Ho - Advanced Intelligent Systems, 2020 - Wiley Online Library
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the
virus that led to the COVID‐19 (Coronavirus Disease 2019) pandemic, has resulted in …
virus that led to the COVID‐19 (Coronavirus Disease 2019) pandemic, has resulted in …
Antimicrobial synergy testing by inkjet printer-assisted automated checkerboard array and manual time-kill methods
T Brennan-Krohn, JE Kirby - Journal of visualized experiments …, 2019 - pmc.ncbi.nlm.nih.gov
As rates of multidrug-resistant (MDR) pathogens continue to rise, outpacing the
development of new antimicrobials, novel approaches to treatment of MDR bacteria are …
development of new antimicrobials, novel approaches to treatment of MDR bacteria are …
Rnd pump-mediated efflux of Amotosalen, a compound used in pathogen inactivation technology to enhance safety of Blood transfusion products, may compromise its …
AB Green, L Chiaraviglio, KA Truelson, KE Zulauf… - Msphere, 2023 - Am Soc Microbiol
Pathogen inactivation is a strategy to improve the safety of transfusion products. The only
pathogen reduction technology for blood products currently approved in the US utilizes a …
pathogen reduction technology for blood products currently approved in the US utilizes a …
[HTML][HTML] In vitro efficacy of ceftazidime-avibactam, aztreonam-avibactam and other rescue antibiotics against carbapenem-resistant Enterobacterales from the Arabian …
Á Sonnevend, A Ghazawi, D Darwish… - International Journal of …, 2020 - Elsevier
Objectives Our aim was to assess the susceptibility of carbapenem-resistant
Enterobacterales (CRE) from the Arabian Peninsula to a broad spectrum of antibiotics …
Enterobacterales (CRE) from the Arabian Peninsula to a broad spectrum of antibiotics …
Prevention and management of carbapenem-resistant Enterobacteriaceae in haematopoietic cell transplantation
DSK Sahitya, A Jandiyal, A Jain… - Therapeutic …, 2021 - journals.sagepub.com
Carbapenem-resistant Enterobacteriaceae (CRE) infections are associated with high
morbidity and mortality rates in haematopoietic cell transplantation (HCT) recipients. Factors …
morbidity and mortality rates in haematopoietic cell transplantation (HCT) recipients. Factors …