Genetics of human primary hypertension: focus on hormonal mechanisms

W Manosroi, GH Williams - Endocrine reviews, 2019 - academic.oup.com
Increasingly, primary hypertension is being considered a syndrome and not a disease, with
the individual causes (diseases) having a common sign—an elevated blood pressure. To …

Genetic factors contributing to hypertension in African‐based populations: A systematic review and meta‐analysis

YY Yako, EV Balti, TE Matsha, A Dzudie… - The Journal of …, 2018 - Wiley Online Library
In a systematic review, the authors explored genetic association studies of essential
hypertension in African populations. Studies reporting on the association of polymorphism …

Association of angiotensin II type 1 receptor (A1166C) gene polymorphism and its increased expression in essential hypertension: a case-control study

S Chandra, R Narang, V Sreenivas, J Bhatia, D Saluja… - PloS one, 2014 - journals.plos.org
Objectives Hypertension is one of the major cardiovascular diseases. It affects nearly 1.56
billion people worldwide. The present study is about a particular genetic polymorphism …

Association of AT1R polymorphism with hypertension risk: An update meta-analysis based on 28,952 subjects

DX Liu, YQ Zhang, B Hu, J Zhang… - Journal of the Renin …, 2015 - journals.sagepub.com
Background: Previous studies have shown that angiotensin II AT1 receptor gene (AT1R)
polymorphisms are associated with the risk for hypertension. However, the results remain …

Correlation between renin-angiotensin system gene polymorphisms and essential hypertension in the Chinese Yi ethnic group

YL Yang, YP Mo, YS He, F Yang, Y Xu… - Journal of the Renin …, 2015 - journals.sagepub.com
Introduction: The renin-angiotensin system (RAS) has been considered to play an important
role in the regulation of blood pressure. This study aimed to investigate the correlation …

Analysis of association of angiotensin II type 1 receptor gene A1166C gene polymorphism with essential hypertension

DN Parchwani, DD Patel, J Rawtani… - Indian Journal of Clinical …, 2018 - Springer
The A/C transversion at 1166 of the angiotensin II Type 1 Receptor (AT1R) gene per se does
not characterize any functional diversity but has been associated with expression of the …

The association between angiotensin II type 1 receptor A1166C gene polymorphism and the risk of essential hypertension: a meta-analysis

JK Fajar, M Susanti, BS Pikir, PNB Saka… - Egyptian Journal of …, 2019 - Springer
Background Since first reported having the association with essential hypertension,
angiotensin II type 1 receptor (AT1R) A1166C was globally investigated worldwide …

[HTML][HTML] Effectiveness of herbs taken concurrently with antihypertensive drugs in managing hypertension and lipid outcomes. A systematic review and meta-analysis.

NS Francis, LY Mooi, S Mat, A Loganathan - Complementary Therapies in …, 2024 - Elsevier
Purpose Hypertension is the primary cause of mortality. Hence globally, there is a growing
interest in complementing antihypertensive drugs with herbs to alleviate blood pressure …

A1166C polymorphism of the angiotensin II type 1 receptor gene contributes to hypertension susceptibility: evidence from a meta-analysis

Y Yang, T Tian, J Lu, H He, K Xing, G Tian - Acta Cardiologica, 2017 - Taylor & Francis
Background The angiotensin II type 1 receptor (AT1R) gene is a prime candidate for
polymorphisms that could contribute to hypertension. A polymorphism in the 3'untranslated …

Effect of interaction between noise and A1166C site of AT1R gene polymorphism on essential hypertension in an iron and steel enterprise workers

J Tong, Y Wang, J Yuan, J Yang, Z Wang… - … of Occupational and …, 2017 - journals.lww.com
Objective: This study aimed to analyze the interaction of Angiotensin II type 1 receptor
(AT1R) gene polymorphism and occupational noise on the occurrence of essential …