Pyrimidines are aromatic heterocyclic compounds that contain two nitrogen atoms at
positions 1 and 3 of the six-membered ring. Numerous natural and synthetic pyrimidines are …

Microbes are unique creatures that adapt to varying lifestyles and environment resistance in
extreme or adverse conditions. The genetic architecture of microbe may bear a significant …

The Biginelli reaction of 3-oxo-N-(2-pyridyl) butanamide with thiourea (or urea) and some
aromatic aldehydes afforded new chemical skeletons containing tetrahydropyrimidine …

A new Cu (II) complex of pyrimidine-4-carboxylic acid was synthesized and characterized
through a combination of single-crystal XRD, Ultraviolet-Visible (UV-Vis), and Fourier …

Breast cancer (BC) is the most common cancer for females and its incidence tends to
increase year by year. Currently, the backbone of therapy for BC is mainly chemotherapy …

Chalcone‐derived pyrimidine is a well‐known heterocyclic compound that is commonly
present in ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) bio‐isosteres …

Background: Methicillin-resistant Staphylococcus aureus (MRSA) is a Gram-positive strain
whose resistance against existing antibiotics is a significant concern for researchers across …

Modified ZnO NPs were synthesized through a sol–gel route with an aromatic capping agent
to provide a highly efficient catalyst, NS-5, for the one-pot multicomponent synthesis of …

The in vitro blood stage antiplasmodial activity of a series of allylated chalcones based on
the licochalcone A as lead molecule was investigated against chloroquine (CQ) sensitive …

Starting compound 1 was synthesized according to reference. Benzylidene thiazole
pyrimidin-3 (5 H)-ones were synthesized reactions of 1 with bromoacetic acid and various …