Role of leukotriene pathway and montelukast in pulmonary and extrapulmonary manifestations of Covid-19: The enigmatic entity
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), the responsible agent for
the coronavirus disease 2019 (Covid-19), has its entry point through interaction with …
the coronavirus disease 2019 (Covid-19), has its entry point through interaction with …
Pluronic F127/Doxorubicin microemulsions: Preparation, characterization, and toxicity evaluations
The development of drug delivery systems minimizing the side effects of conventional
chemotherapy is one of the major challenges in the field of biomaterials for cancer treatment …
chemotherapy is one of the major challenges in the field of biomaterials for cancer treatment …
Anti-inflammatory, anti-apoptotic, and antioxidant roles of honey, royal jelly, and propolis in suppressing nephrotoxicity induced by doxorubicin in male albino rats
HK Mohamed, MA Mobasher, RA Ebiya, MT Hassen… - Antioxidants, 2022 - mdpi.com
Nephrotoxicity is one of the limiting factors for using doxorubicin (DOX). Honey, propolis,
and royal jelly were evaluated for their ability to protect against nephrotoxicity caused by …
and royal jelly were evaluated for their ability to protect against nephrotoxicity caused by …
[HTML][HTML] Interference with megalin expression/endocytic function by montelukast mitigates gentamicin nephrotoxicity: Downregulation of ClC-5 expression
AA Azouz, DA Hanna, AA Abo-Saif… - Saudi Pharmaceutical …, 2022 - Elsevier
Megalin receptor-mediated endocytosis participates a crucial role in gentamicin (GM)
uptake, accumulation, and toxicity. In this study, we investigated the potential effects of …
uptake, accumulation, and toxicity. In this study, we investigated the potential effects of …
Montelukast ameliorates doxorubicin-induced cardiotoxicity via modulation of p-glycoprotein and inhibition of ROS-mediated TNF-α/NF-κB pathways
HM Hafez, H Hassanein - Drug and Chemical Toxicology, 2022 - Taylor & Francis
Doxorubicin (DOX) cardiotoxicity remains an obstacle to clinical use. The current study
examined the possible role of montelukast (ML), which is a cysteinyl leukotrienes receptor …
examined the possible role of montelukast (ML), which is a cysteinyl leukotrienes receptor …
Leukotriene receptor antagonist, montelukast ameliorates L-Name-induced pre-eclampsia in rats through suppressing the IL-6/Jak2/STAT3 signaling pathway
WY Abdelzaher, G Mostafa-Hedeab, HA Bahaa… - Pharmaceuticals, 2022 - mdpi.com
Aims: To investigate the potential protective role of montelukast (Mont) in the pre-eclampsia
rat model induced by L-NG-Nitro arginine methyl ester (L-NAME). Methods and materials …
rat model induced by L-NG-Nitro arginine methyl ester (L-NAME). Methods and materials …
The renoprotective potential of montelukast: a scoping review
R Sarmadian, A Gilani, S Mehrtabar… - Annals of Medicine …, 2024 - journals.lww.com
Methods: The authors conducted a scoping review using PubMed, Scopus, and Web of
Science databases to identify relevant studies investigating the impact of montelukast on …
Science databases to identify relevant studies investigating the impact of montelukast on …
Synergistic impacts of Montelukast and Klotho against doxorubicin-induced cardiac toxicity in Rats
HA Elnoury, SA Elgendy, SH Baloza… - Toxicology …, 2022 - academic.oup.com
Doxorubicin (DOX) is a powerful antitumor agent with a well-known cardiaotoxic side effects.
In the current study, the ameliorative combined impacts of montelukast (Mont) and Klotho …
In the current study, the ameliorative combined impacts of montelukast (Mont) and Klotho …
Protective effect of leukotriene receptor antagonist, montelukast, against cyclophosphamide-induced placental toxicity via modulation of NLRP3/IL-1β signaling …
WY Abdelzaher, SA Ibrahim, SAW Abdel-Gaber… - International …, 2024 - Elsevier
Backgrounds & aim Placental insufficiency is a serious complication that affects pregnancy
and fetal growth. Cyclophosphamide (CYC) is considered one of the chemotherapeutic …
and fetal growth. Cyclophosphamide (CYC) is considered one of the chemotherapeutic …
Modulation of autophagy and transient receptor potential vanilloid 4 channels by montelukast in a rat model of hemorrhagic cystitis
RA Elrashidy, RA Hasan - Life Sciences, 2021 - Elsevier
Aims Hemorrhagic cystitis (HC) is a major urotoxic complication of cyclophosphamide (CPA)
therapy. This study investigated the uroprotective effect of montelukast on CPA-induced HC …
therapy. This study investigated the uroprotective effect of montelukast on CPA-induced HC …