Cell-penetrating antimicrobial peptides with anti-infective activity against intracellular pathogens

GS Cruz, AT Santos, EHS Brito, G Radis-Baptista - Antibiotics, 2022 - mdpi.com
Cell-penetrating peptides (CPPs) are natural or engineered peptide sequences with the
intrinsic ability to internalize into a diversity of cell types and simultaneously transport …

Enhancing the Antimicrobial Properties of Peptides through Cell-Penetrating Peptide Conjugation: A Comprehensive Assessment

SV Kravchenko, PA Domnin, SY Grishin… - International Journal of …, 2023 - mdpi.com
Combining antimicrobial peptides (AMPs) with cell-penetrating peptides (CPPs) has shown
promise in boosting antimicrobial potency, especially against Gram-negative bacteria. We …

Nanogel delivery systems for cationic peptides: More than a 'One Size Fits All'solution

SN Kłodzińska, Q Wang, N Molchanova… - Journal of Colloid and …, 2024 - Elsevier
Self-assembled hyaluronic acid-based nanogels are versatile drug carriers due to their
biodegradable nature and gentle preparation conditions, making them particularly …

Harnessing the Therapeutic Potential of Antimicrobial Peptides for Cancers: State of the Art

M Mahjoubin-Tehran, S Rezaei… - Current Topics in …, 2023 - ingentaconnect.com
Despite significant breakthroughs in cancer treatment, cancer remains a serious global
health concern that takes thousands of lives each year. Still, drug resistance and adverse …

Antimicrobial Peptides as Broad-Spectrum Therapeutics: Computational Analysis to Identify Universal Physical-Chemical Features Responsible for Multitarget Activity

A Medvedeva, C Vasnetsov, V Vasnetsov… - The Journal of …, 2024 - ACS Publications
Antimicrobial peptides (AMPs) hold significant potential as broad-spectrum therapeutics due
to their ability to target a variety of different pathogens, including bacteria, fungi, and viruses …

Characterization and evaluation of cell-penetrating activity of brevinin-2R: an amphibian skin antimicrobial peptide

S Nooranian, R Kazemi Oskuee, A Jalili - Molecular Biotechnology, 2022 - Springer
Natural peptides have been the source of some important tools to address challenges in
protein therapy of diseases. Bypassing cell plasma membrane has been a bottleneck in the …

Rational Drug Design and Inhibitory Potential of Class II Bacteriocins: Novel Strategies for Mitigating Antibiotic Resistance

CEH Rosenkilde - 2023 - orbit.dtu.dk
Context: Since their commercial usage in the early 20th century, antibiotics have been a
transformative force in the management of infectious diseases, substantially lowering …

[PDF][PDF] The recombinant hybrid peptide LL-37_Renalexin exhibits antimicrobial activity at lower MICs than its counterpart single peptides

JK Narh - 2023 - eprints.uanl.mx
An alarming global public health and economic peril has been the emergence of antibiotic
resistance resulting from clinically relevant bacteria pathogens, including Enterococcus …

[引用][C] Development and application of antimicrobial peptides based on sC18 to fight antibiotic resistance and bacterial adhesion

MG Drexelius - 2023 - Universität zu Köln