Cancer progression often benefits from the selective conditions present in the tumour
microenvironment, such as the presence of cancer-associated fibroblasts (CAFs) …

Calcium (Ca2+) functions as a second messenger that is critical in regulating fundamental
physiological functions such as cell growth/development, cell survival, neuronal …

Genomic instability is a primary cause and fundamental feature of human cancer. However,
all cancer cell genotypes generally translate into several common pathophysiological …

The interplay between Ca 2+ and reactive oxygen species (ROS) signaling pathways is well
established, with reciprocal regulation occurring at a number of subcellular locations. Many …

Calcium (Ca2+) homeostasis is essential for cell maintenance since this ion participates in
many physiological processes. For example, the spatial and temporal organization of Ca2+ …

Autophagy is a cellular process in which the cell degrades and recycles its own constituents.
Given the crucial role of autophagy in physiology, deregulation of autophagic machinery is …

In neurons, Ca 2+ is essential for a variety of physiological processes that regulate gene
transcription to neuronal growth and their survival. 1-methyl-4-phenyl-1, 2, 3, 6 …

Adriamycin is a first-line chemotherapy agent against cancer, but the development of
resistance has become a major problem. Although autophagy is considered to be an …

Breast cancer is one of the most frequent cancer types worldwide and the first cause of
cancer-related deaths in women. Although significant therapeutic advances have been …

Stromal interaction molecules (STIMs), including STIM1 and STIM2, are single-pass
transmembrane proteins that are located predominantly in the endoplasmic reticulum (ER) …