Prostate cancer (PCa) affects millions of men globally. Due to advances in understanding
genomic landscapes and biological functions, the treatment of PCa continues to improve …

The discovery of kisspeptin as a critical central regulatory factor of GnRH release has given
people a novel understanding of the neuroendocrine regulation in human reproduction …

Background Endometriosis is a chronic, estrogen-dependent condition that causes
dysmenorrhea and pelvic pain. Elagolix, an oral, nonpeptide, gonadotropin-releasing …

Despite the progress made during the last two decades in the surgery and chemotherapy of
ovarian cancer, more than 70% of advanced patients are with recurrent cancer and …

Gonadotropin-releasing hormone (GnRH) analogues are commonly used in clinical practice
to prevent premature luteinizing hormone (LH) surge during In-Vitro Fertilization/Intra …

Adjuvant gonadotropin‐releasing hormone analogues for the prevention of chemotherapy‐induced
premature ovarian failure in premenopausal women - Chen, H - 2019 | Cochrane Library Skip …

Uterine adenomyosis is a commonly encountered estrogen-dependent disease in
reproductive-age women, causing heavy menstrual bleeding, intense pelvic pain, and …

Context: Elagolix is a nonpeptide, oral gonadotropin-releasing hormone (GnRH) antagonist
being developed for sex-hormone–dependent diseases in women. Objective: We evaluated …

Thyroid disorders are the most common endocrine problems in women. In most of the cases,
thyroid can lead to infertility or miscarriages. The etiology of infertility is multifactorial with …

The mechanisms underlying the initiation of puberty, one of the cornerstones of human
evolution, have not been fully elucidated as yet. However, recently, an accumulating body of …