Abstract Pluronic (PEO-PPO-PEO) block copolymers can form nano-sized micelles with a
structure composed of a hydrophobic PPO core and hydrophilic PEO shell layer. Pluronics …

The formation of polymeric micelles in aqueous environments through the self-assembly of
amphiphilic polymers can provide a versatile platform to increase the solubility and …

Triple‐negative breast cancer (TNBC) is still the most aggressive cancer in women.
Combination chemotherapy holds great potential for cancer therapy; however, the off‐target …

Nitroxide-mediated polymerization (NMP) is a reversible-deactivation radical polymerization
technique (RDRP) that facilitates the synthesis of well-defined and complex macromolecular …

Stimuli-responsive nanotechnology-mediated drug co-delivery system is a notable strategy
to improve access of the systemically administered chemotherapeutics to the tumors. Herein …

We recently constructed a multicellular spheroid model of pancreatic tumor based on a triple
co-culture of cancer cells, fibroblasts and endothelial cells and characterized by the …

The precise design of polymers with well-defined end functionality has received great
interest for synthesizing polymeric materials with advanced or distinctive properties. In the …

Purpose: Many natural agents have a high anticancer potential, and their combination may
be advantageous for improved anticancer effects. Such agents, however, often are not water …

Radical ring-opening polymerization (rROP) has received renewed attention to incorporate
cleavable linkages into the backbones of vinyl polymers, especially from cyclic ketene …

Currently, the therapeutic performance of traditional mono-chemotherapy on cancers
remains unsatisfactory because of the tumor heterogeneity and multidrug resistance. In light …