MitoTool: a web server for the analysis and retrieval of human mitochondrial DNA sequence variations

L Fan, YG Yao - Mitochondrion, 2011 - Elsevier
MitoTool, a web-based bioinformatics platform, is designed for deciphering human
mitochondrial DNA (mtDNA) data in batch mode. The platform has advantages in (i) parsing …

The mitochondrial genome, a growing interest inside an organelle

M Crimi, R Rigolio - International journal of nanomedicine, 2008 - Taylor & Francis
Mitochondria are semi-autonomously reproductive organelles within eukaryotic cells
carrying their own genetic material, called the mitochondrial genome (mtDNA). Until some …

The importance of integrating SNP and cheminformatics resources to pharmacogenomics

HW Chang, LY Chuang, MT Tsai… - Current Drug …, 2012 - ingentaconnect.com
Single nucleotide polymorphisms (SNPs) are the most frequent variants in many genes and
are promising markers in relation to drug responses in pharmacogenomics studies. In this …

[HTML][HTML] Conserved PCR primer set designing for closely-related species to complete mitochondrial genome sequencing using a sliding window-based PSO algorithm

CH Yang, HW Chang, CH Ho, YC Chou, LY Chuang - PLoS One, 2011 - journals.plos.org
Background Complete mitochondrial (mt) genome sequencing is becoming increasingly
common for phylogenetic reconstruction and as a model for genome evolution. For long …

A novel teaching-learning-based optimization for improved mutagenic primer design in mismatch PCR-RFLP SNP genotyping

YH Cheng - IEEE/ACM Transactions on Computational Biology …, 2015 - ieeexplore.ieee.org
Many single nucleotide polymorphisms (SNPs) for complex genetic diseases are genotyped
by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in …

Prim-SNPing: a primer designer for cost-effective SNP genotyping

HW Chang, LY Chuang, YH Cheng, YC Hung… - …, 2009 - Taylor & Francis
Many kinds of primer design (PD) software tools have been developed, but most of them
lack a single nucleotide polymorphism (SNP) genotyping service. Here, we introduce the …

Effective natural PCR-RFLP primer design for SNP genotyping using teaching-learning-based optimization with elite strategy

YH Cheng, CN Kuo, CM Lai - IEEE transactions on …, 2016 - ieeexplore.ieee.org
SNP (single nucleotide polymorphism) genotyping is the determination of genetic variations
of SNPs between members of a species. In many laboratories, PCR-RFLP (polymerase …

Mutagenic primer design for mismatch PCR-RFLP SNP genotyping using a genetic algorithm

CH Yang, YH Cheng, CH Yang… - IEEE/ACM Transactions …, 2012 - ieeexplore.ieee.org
Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) is useful
in small-scale basic research studies of complex genetic diseases that are associated with …

Associate PCR-RFLP assay design with SNPs based on genetic algorithm in appropriate parameters estimation

LY Chuang, YH Cheng, CH Yang… - IEEE Transactions on …, 2013 - ieeexplore.ieee.org
Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) is a
commonly used laboratory technique and useful in small-scale basic research studies of …

[PDF][PDF] A natural PCR-RFLP primer design for SNP genotyping using a genetic algorithm

CH Yang, YH Cheng, LY Chuang - … MultiConference of Engineers …, 2010 - researchgate.net
Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) is a
commonly used laboratory technique and useful in small-scale basic research studies of …