Every cell in a living organism is constantly exposed to physical and chemical factors which
damage the molecular structure of proteins, lipids, and nucleic acids. Cellular DNA lesions …

In recent years, the field of drug delivery has witnessed remarkable progress, driven by the
quest for more effective and precise therapeutic interventions. Among the myriad strategies …

DNA is an important target for the treatment of multiple pathologies, most notably cancer. In
particular, DNA intercalators have often been used as anticancer drugs. However, despite …

Polymer nanoparticles are vehicles used for delivery of hydrophobic anti-cancer drugs, like
doxorubicin, paclitaxel or chemopreventors like quercetin (Q). The present study deals with …

Flavonoids are dietary intakes which are bestowed with several health benefits. The most
studied property of flavonoids is their antioxidant efficacy. Among the chosen flavonoids …

The health benefits stemming from green tea are well known, but the exact mechanism of its
biological activity is not elucidated. Epicatechin (EC) and epicatechin gallate (ECG) are two …

Intelligent transfer of drugs to target cells is one of the important challenges in
pharmaceuticals and disease treatment. Based on this, various investigations have been …

Normal human genomic DNA (N-DNA) and mutated DNA (M-DNA) from K562 leukemic cells
show different thermodynamic properties and binding affinities on interaction with anticancer …

Targeted drug delivery system delivers drug to diseased organ, tissue, or cells by utilizing
some physical means and biological properties, such as pH gradients in the intestine …

Chemoresistance poses a significant obstacle to the treatment of breast cancer patients. The
increased capacity of DNA damage repair is one of the mechanisms underlying …