Diagnosis and treatment of unruptured intracranial aneurysms and aneurysmal subarachnoid hemorrhage

RG Tawk, TF Hasan, CE D'Souza, JB Peel… - Mayo Clinic …, 2021 - Elsevier
Unruptured intracranial aneurysms (UIAs) are commonly acquired vascular lesions that form
an outpouching of the arterial wall due to wall thinning. The prevalence of UIAs in the …

Unruptured intracranial aneurysms: development, rupture and preventive management

N Etminan, GJ Rinkel - Nature Reviews Neurology, 2016 - nature.com
Saccular unruptured intracranial aneurysms (UIAs) have a prevalence of 3% in the adult
population, and are being increasingly detected because of improved quality and higher …

Guidelines for the management of patients with unruptured intracranial aneurysms: a guideline for healthcare professionals from the American Heart Association …

BG Thompson, RD Brown Jr, S Amin-Hanjani… - Stroke, 2015 - Am Heart Assoc
Purpose—The aim of this updated statement is to provide comprehensive and evidence-
based recommendations for management of patients with unruptured intracranial …

Unruptured intracranial aneurysms: epidemiology, natural history, management options, and familial screening

RD Brown, JP Broderick - The Lancet Neurology, 2014 - thelancet.com
Intracranial saccular or berry aneurysms are common, occurring in about 1–2% of the
population. Unruptured intracranial aneurysms are increasingly being detected as cross …

Unruptured cerebral aneurysms: evaluation and management

N Ajiboye, N Chalouhi, RM Starke… - The Scientific World …, 2015 - Wiley Online Library
The evolution of imaging techniques and their increased use in clinical practice have led to
a higher detection rate of unruptured intracranial aneurysms. The diagnosis of an …

Intracranial aneurysms: Review of current science and management

G Toth, R Cerejo - Vascular Medicine, 2018 - journals.sagepub.com
Unruptured intracranial aneurysms often have a relatively benign clinical course. Frequently,
they are found incidentally during workup for an underlying, possibly related or unrelated …

Unruptured intracranial aneurysms: contemporary data and management

KAM Hackenberg, D Hänggi, N Etminan - Stroke, 2018 - Am Heart Assoc
Patient-related, modifiable risk factors—in addition to arterial hypertension, established in
PHASES—are current cigarette smoking and heavy alcohol consumption. 14, 15 For …

Intracranial aneurysms: pathology, genetics, and molecular mechanisms

Z Xu, YN Rui, JP Hagan, DH Kim - Neuromolecular medicine, 2019 - Springer
Intracranial aneurysms (IA) are local dilatations in cerebral arteries that predominantly affect
the circle of Willis. Occurring in approximately 2–5% of adults, these weakened areas are …

Genetics of intracranial aneurysms

MK Bakker, YM Ruigrok - Stroke, 2021 - Am Heart Assoc
Rupture of an intracranial aneurysm leads to aneurysmal subarachnoid hemorrhage, a
severe type of stroke which is, in part, driven by genetic variation. In the past 10 years …

Smooth muscle cells and the formation, degeneration, and rupture of saccular intracranial aneurysm wall—a review of current pathophysiological knowledge

J Frösen - Translational stroke research, 2014 - Springer
Subarachnoid hemorrhage or intracerebral hemorrhage caused by rupture of a saccular
intracranial aneurysm (sIA) is often fatal and causes significant loss of productive live years …