Twenty of the last one hundred years of vitamin D research have involved investigations of
the brain as a target organ for this hormone. Our group was one of the first to investigate …

Increasingly vitamin D deficiency is being associated with a number of psychiatric
conditions. In particular for disorders with a developmental basis, such as autistic spectrum …

It has been 20 years since we first proposed vitamin D as a “possible” neurosteroid.(1) Our
work over the last two decades, particularly results from our cellular and animal models, has …

Sjögren's syndrome (SS) is a systemic progressive autoimmune disease characterized by a
complex pathogenesis requiring a predisposing genetic background and involving immune …

In recent years, emerging evidence has linked vitamin D not only to its known effects on
calcium and bone metabolism, but also to many chronic illnesses involving neurocognitive …

Vitamin D is a fat-soluble secosteroid that exerts its effects by binding to the vitamin D
receptor (VDR), through which it directly and indirectly modulates the expression of …

About 50 million of the US adult population suffer from chronic pain. It is a complex disease
in its own right for which currently available analgesics have been deemed woefully …

Vitamin D deficiency is believed to affect between 35 and 55% of the world's population,
making it a hidden pandemic. In addition to its role in bone and calcium homeostasis …

Previously, we demonstrated i) that ergocalciferol (vitamin D2) increases axon diameter and
potentiates nerve regeneration in a rat model of transected peripheral nerve and ii) that …

Over the last decade a convergent body of evidence has emerged from epidemiology,
animal experiments and clinical trials which links low vitamin D status with a range of …