[HTML][HTML] mTOR function and therapeutic targeting in breast cancer

SH Hare, AJ Harvey - American journal of cancer research, 2017 - ncbi.nlm.nih.gov
The mTOR pathway was discovered in the late 1970s after the compound and natural
inhibitor of mTOR, rapamycin was isolated from the bacterium Streptomyces hygroscopicus …

Novel mechanism of cannabidiol-induced apoptosis in breast cancer cell lines

AS Sultan, MA Marie, SA Sheweita - The Breast, 2018 - Elsevier
Studies have emphasized an antineoplastic effect of the non-psychoactive, phyto-
cannabinoid, Cannabidiol (CBD). However, the molecular mechanism underlying its …

Monitoring Early Breast Cancer Response to Neoadjuvant Therapy Using H‐Scan Ultrasound Imaging: Preliminary Preclinical Results

M Khairalseed, K Javed, G Jashkaran… - … of Ultrasound in …, 2019 - Wiley Online Library
Objective H‐scan imaging is a new ultrasound technique used to visualize the relative size
of acoustic scatterers. The purpose of this study was to evaluate the use of H‐scan …

Anticancer Evaluation of Methoxy Poly(Ethylene Glycol)-b-Poly(Caprolactone) Polymeric Micelles Encapsulating Fenbendazole and Rapamycin in Ovarian Cancer

YB Shin, JY Choi, DH Shin, JW Lee - International Journal of …, 2023 - Taylor & Francis
Purpose We aimed to inhibit ovarian cancer (OC) development by interfering with
microtubule polymerization and inhibiting mTOR signaling. To achieve this, previously …

Three-dimensional H-scan ultrasound imaging of early breast cancer response to neoadjuvant therapy in a murine model

H Tai, J Song, J Li, S Reddy, M Khairalseed… - Investigative …, 2022 - journals.lww.com
Objectives Three-dimensional (3D) H-scan is a new ultrasound (US) technique that images
the relative size of acoustic scatterers. The goal of this research was to evaluate use of 3D H …

Morusin suppresses breast cancer cell growth in vitro and in vivo through C/EBPβ and PPARγ mediated lipoapoptosis

H Li, Q Wang, L Dong, C Liu, Z Sun, L Gao… - Journal of Experimental & …, 2015 - Springer
Background Breast cancer is the most fatal malignant cancer among women, the
conventional therapeutic modalities of it are limited. Morusin possesses cytotoxicity against …

Effect of sesamin on apoptosis and cell cycle arrest in human breast cancer mcf-7 cells

AC Siao, CW Hou, YH Kao… - Asian Pacific Journal of …, 2015 - journal.waocp.org
Dietary prevention has been known to reduce breast cancer risk. Sesamin is one of the
major components insesame seeds and has been widely studied and proven to have anti …

Induced cell cycle arrest in triple-negative breast cancer by combined treatment of itraconazole and rapamycin

HT Wu, CL Li, ZX Fang, WJ Chen, WT Lin… - Frontiers in …, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is the aggressive molecular type of breast carcinoma,
with a high metastasis/relapse incidence and cancer-related death rate, due to lack of …

Anesthetic effects of isoflurane and the molecular mechanism underlying isoflurane‑inhibited aggressiveness of hepatic carcinoma

J Hu, J Hu, H Jiao, Q Li - Molecular Medicine Reports, 2018 - spandidos-publications.com
Anesthesia is produced by drugs or other methods, and refers to the attenuation of pain via
reversible suppression of neuronal transmission in the central and peripheral nervous …

Anti-proliferative and apoptotic effects of dendrosomal farnesiferol C on gastric cancer cells

Z Aas, E Babaei, MAH Feizi… - Asian Pacific Journal of …, 2015 - koreascience.kr
Farnesiferol C is a natural compound with various anti-cancer properties that belongs to the
class of sesquiterpene coumarins. However, the low bioavailability of farnesiferol C limits its …