[HTML][HTML] Biomarkers of osteosarcoma, chondrosarcoma, and Ewing sarcoma
Osteosarcoma is the most frequent malignant bone neoplasm, followed by chondrosarcoma
and Ewing sarcoma. The diagnosis of bone neoplasms is generally made through …
and Ewing sarcoma. The diagnosis of bone neoplasms is generally made through …
The adolescent and young adult with cancer: State of the art-bone tumors
N Rainusso, LL Wang, JT Yustein - Current oncology reports, 2013 - Springer
Primary malignant bone tumors in the pediatric to young adult populations are relatively
uncommon and account for about 6% of all cancers in those less than 20 years old [1] and …
uncommon and account for about 6% of all cancers in those less than 20 years old [1] and …
ETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation
The EWS-FLI1 fusion oncoprotein deregulates transcription to initiate the paediatric cancer
Ewing sarcoma. Here we used a domain-focused CRISPR screen to implicate the …
Ewing sarcoma. Here we used a domain-focused CRISPR screen to implicate the …
[HTML][HTML] A molecular function map of Ewing's sarcoma
Background EWS-FLI1 is a chimeric ETS transcription factor that is, due to a chromosomal
rearrangement, specifically expressed in Ewing's sarcoma family tumors (ESFT) and is …
rearrangement, specifically expressed in Ewing's sarcoma family tumors (ESFT) and is …
[HTML][HTML] Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model
Ewing sarcoma (ES) involves a tumor-specific chromosomal translocation that produces the
EWS-FLI1 protein, which is required for the growth of ES cells both in vitro and in vivo …
EWS-FLI1 protein, which is required for the growth of ES cells both in vitro and in vivo …
[HTML][HTML] Recapitulating the size and cargo of tumor exosomes in a tissue-engineered model
A Villasante, A Marturano-Kruik, SR Ambati, Z Liu… - Theranostics, 2016 - ncbi.nlm.nih.gov
There is a growing interest in the pivotal role of exosomes in cancer and in their use as
biomarkers. However, despite the importance of the microenvironment for cancer initiation …
biomarkers. However, despite the importance of the microenvironment for cancer initiation …
Mesenchymal stem cells and the origin of Ewing′ s sarcoma
PP Lin, Y Wang, G Lozano - Sarcoma, 2011 - Wiley Online Library
The origin of Ewing′ s sarcoma is a subject of much debate. Once thought to be derived
from primitive neuroectodermal cells, many now believe it to arise from a mesenchymal stem …
from primitive neuroectodermal cells, many now believe it to arise from a mesenchymal stem …
[HTML][HTML] Ewing Sarcoma, an enigmatic malignancy of likely progenitor cell origin, driven by transcription factor oncogenic fusions
P Jedlicka - International journal of clinical and experimental …, 2010 - ncbi.nlm.nih.gov
Since its first description by James Ewing in 1921, Ewing Sarcoma has been a cryptic
malignancy. A poorly differentiated tumor of uncertain histogenesis and aggressive biologic …
malignancy. A poorly differentiated tumor of uncertain histogenesis and aggressive biologic …
An approach to renal masses in pediatrics
Renal masses in children may be discovered during routine clinical examination or
incidentally during the course of diagnostic or therapeutic procedures for other causes …
incidentally during the course of diagnostic or therapeutic procedures for other causes …
Blocking the road, stopping the engine or killing the driver? Advances in targeting EWS/FLI-1 fusion in Ewing sarcoma as novel therapy
H Kovar - Expert opinion on therapeutic targets, 2014 - Taylor & Francis
Introduction: Ewing sarcoma (ES) represents the paradigm of an aberrant E-twenty-six (ETS)
oncogene-driven cancer. It is characterized by specific rearrangements of one of five …
oncogene-driven cancer. It is characterized by specific rearrangements of one of five …