Acromegaly is associated with an enhanced mortality, with cardiovascular and respiratory
complications representing not only the most frequent comorbidities but also two of the main …

Cardiovascular complications are frequent in acromegalic patients. Several studies reported
increased prevalence of traditional cardiovascular risk factors and early development of …

Acromegaly is characterized by Growth Hormone (GH) and Insulin-like Growth Factor 1 (IGF-
1) excess. Uncontrolled acromegaly is associated with a strongly increased risk of …

Secreting pituitary adenomas that cause acromegaly and Cushing's disease, as well as
prolactinomas and thyrotroph adenomas, are uncommon, usually benign, slow-growing …

Acromegaly is a rare, chronic disease whose clinical manifestations are the consequence of
growth hormone (GH) and insulinlike growth factor (IGF) 1 excess that is usually caused by a …

Growth hormone (GH) and insulin like growth factor-1 (IGF-1) excess induce well-known
deleterious effects on the cardiovascular system, especially after long-term exposition …

Objective Multiple studies investigated preclinical markers of peripheral vascular damage in
acromegaly (ACRO) reporting discordant results. The aim of this study was to run a meta …

Purpose Data regarding atherosclerosis in acromegaly is controversial in literature. We
aimed to investigate the markers of early atherosclerosis, oxidative stress, inflammation and …

Purpose Acromegaly is associated with increased cardiovascular morbidity and mortality
when inadequately treated, which may be secondary to associated comorbidities or to direct …

A considerable amount of data supports a 1.8-7.4-fold increased mortality associated with
Cushing's syndrome (CS). This is attributed to a high occurrence of several cardiovascular …