In multicellular organisms, angiogenesis, the formation of new blood vessels from pre-
existing ones, is an essential process for growth and development. Different mechanisms …

Atherosclerosis is a silent chronic vascular pathology that is the cause of the majority of
cardiovascular ischaemic events. The evolution of vascular disease involves a combination …

Atherosclerosis is the most common form of vascular disease and constitutes the major
cause of death, with 17.5 million related deaths annually (31% of global mortality). 1 …

There have been few fundamental improvements in clinical X-ray contrast agents in more
than 25 years, and the chemical platform of tri-iodobenzene has not changed. Current …

Platelets contribute to processes beyond thrombus formation and may play a so far
underestimated role as an immune cell in various circumstances. This review outlines …

Rupture of atherosclerotic plaque has been identified as the proximate event in the majority
of cases of acute ischemic syndromes. Plaque rupture exposes thrombogenic components …

Background—Growth of atherosclerotic plaques is accompanied by neovascularization from
vasa vasorum microvessels extending through the tunica media into the base of the plaque …

Coronary neovascularization may also accompany the early process of vessel wall
remodeling, as observed in hypercholesterolemic swine. 16 In this animal model …

Background—Neovascularization within the intima of human atherosclerotic lesions is well
described, but its role in the progression of atherosclerosis is unknown. In this report, we first …

Vascular endothelial growth factor (VEGF) can promote angiogenesis but may also exert
certain effects to alter the rate of atherosclerotic plaque development. To evaluate this …