Tendon is an intricately organized connective tissue that efficiently transfers muscle force to
the bony skeleton. Its structure, function, and physiology reflect the extreme, repetitive …

Tendon is a bradytrophic and hypovascular tissue, hence, healing remains a major
challenge. The molecular key events involved in successful repair have to be unravelled to …

Peripheral neurons terminate at the surface of tendons partly to relay nociceptive pain
signals; however, the role of peripheral nerves in tendon injury and repair remains unclear …

Nature has created many perfect helical microstructures, including DNA, collagen fibrils, and
helical blood vessels, to achieve unique physiological functions. While previous studies …

Purpose Functional weight-bearing mobilization may improve repair of Achilles tendon
rupture (ATR), but the underlying mechanisms and outcome were unknown. We …

Sex differences have been reported for diseases of the musculoskeletal system (MSK) as
well as the risk for injuries to tissues of the MSK system. For females, some of these occur …

Although the functions of the peripheral nervous system in whole body homeostasis and
sensation have been understood for many years, recent investigation has uncovered new …

Heart rate variability (HRV) is a popular tool for monitoring training adaptation and readiness
in athletes, but it also has the potential to indicate early signs of somatic tissue overload prior …

Soft tissue injuries (STIs) affect patients of all age groups and represent a common
worldwide clinical problem, resulting from conditions including trauma, infection, cancer and …

Accurate detection and prevention of overuse musculoskeletal injuries is limited by the
nature of somatic tissue injury. In the pathogenesis of overuse injuries, it is well recognized …