There are more than 30 species of Glycyrrhiza genus extensively spread worldwide. It was
the most prescribed herb in Ancient Egyptian, Roman, Greek, East China, and the West from …

Ethnopharmacological relevance With high mortality and morbidity rates, lung cancer (LC)
has become one of the major threats to human health. The treatment strategies for LC …

Ethnopharmacological relevance Licorice has been commonly used in traditional Chinese
medicine for treatment of gastric, liver, and respiratory disease conditions for more than two …

Licochalcone A (LA), a useful and valuable flavonoid, is isolated from Glycyrrhiza uralensis
Fisch. ex DC. and widely used clinically in traditional Chinese medicine. We systematically …

Cancer is a condition caused by many mechanisms (genetic, immune, oxidation, and
inflammatory). Anticancer therapy aims to destroy or stop the growth of cancer cells …

Lung cancer is the leading cause of cancer‐related mortality both in men and women and
accounts for 18.4% of all cancer‐related deaths. Although advanced therapy methods have …

The rise of cancer immunotherapy, particularly the use of immune checkpoint inhibitors
(ICIs), has significantly changed the clinical treatment paradigm for patients with cancer. The …

Endoplasmic reticulum (ER) stress is known to influence various cellular functions, including
cell cycle progression. Although it is well known how ER stress inhibits cell cycle …

There is no doubt that significant progress has been made in tumor therapy in the past
decades. However, the discovery of new molecules with potential antitumor properties still …

We investigated the anti-cancer activity of Licochalcone A (LCA), extracted from licorice root.
LCA inhibited the proliferation of HepG 2 cells with IC 50 (65.96 μM) for 24 h and IC 50 …