Laboratory diagnostic tools for syphilis: current status and future prospects

Y Luo, Y Xie, Y Xiao - Frontiers in cellular and infection microbiology, 2021 - frontiersin.org
With the increasing number of patients infected with syphilis in the past 20 years, early
diagnosis and early treatment are essential to decline syphilis prevalence. Owing to its …

Recent trends in the serologic diagnosis of syphilis

MG Morshed, AE Singh - Clinical and vaccine immunology, 2015 - Am Soc Microbiol
Complexities in the diagnosis of syphilis continue to challenge clinicians. While direct tests
(eg, microscopy or PCR) are helpful in early syphilis, the mainstay of diagnosis remains …

[PDF][PDF] 2020 European guideline on the management of syphilis.

M Janier, M Unemo, N Dupin, GS Tiplica… - Journal of the European …, 2021 - cnr-ist.fr
2020 European guideline on the management of syphilis Page 1 GUIDELINES 2020 European
guideline on the management of syphilis M. Janier,1,* M. Unemo,2 N. Dupin,3 GS Tiplica,4 M …

2014 European guideline on the management of syphilis

M Janier, V Hegyi, N Dupin, M Unemo… - Journal of the …, 2014 - Wiley Online Library
Background Syphilis remains a major public health problem in Europe (both in Eastern
Europe since the 1990's and in Western Europe since the re‐emergence of the disease in …

A smartphone dongle for diagnosis of infectious diseases at the point of care

T Laksanasopin, TW Guo, S Nayak… - Science translational …, 2015 - science.org
This work demonstrates that a full laboratory-quality immunoassay can be run on a
smartphone accessory. This low-cost dongle replicates all mechanical, optical, and …

[HTML][HTML] Syphilis: Re-emergence of an old foe

LV Stamm - Microbial Cell, 2016 - ncbi.nlm.nih.gov
Syphilis is caused by infection with Treponema pallidum subsp. pallidum, a not-yet-
cultivable spiral-shaped bacterium that is usually transmitted by sexual contact with an …

A suite of PCR-LwCas13a assays for detection and genotyping of Treponema pallidum in clinical samples

W Chen, H Luo, L Zeng, Y Pan, JB Parr, Y Jiang… - Nature …, 2022 - nature.com
The performance of commonly used assays for diagnosis of syphilis varies considerably
depending on stage of infection and sample type. In response to the need for improved …

Discordant results from reverse sequence syphilis screening--five laboratories, United States, 2006-2010.

JD Radolf, G Bolan, IU Park, JM Chow… - MMWR: Morbidity & …, 2011 - search.ebscohost.com
The article discusses the results of an analysis conducted by the US Centers for Disease
Control and Prevention (CDC) on reverse sequence screening for syphilis from 2006 to …

Syphilis in the modern era: an update for physicians

SE Cohen, JD Klausner, J Engelman… - Infectious Disease …, 2013 - id.theclinics.com
Syphilis is caused by infection with the spirochetal bacterium Treponema subspecies
pallidum. T pallidum is a highly motile coiled organism with tapering ends and 6 to 14 …

Screening for syphilis: updated evidence report and systematic review for the US Preventive Services Task Force

AG Cantor, M Pappas, M Daeges, HD Nelson - Jama, 2016 - jamanetwork.com
Importance Screening for syphilis infection is currently recommended for high-risk
individuals, including those with previous syphilis infection, an infected sexual partner, HIV …