Chemoenzymatic catalysis, by definition, involves the merging of sequential reactions using
both chemocatalysis and biocatalysis, typically in a single reaction vessel. A major …

The bottom-up assembly of biological and chemical components opens exciting
opportunities to engineer artificial vesicular systems for applications with previously unmet …

Enzymes are versatile catalysts and their synthetic potential has been recognized for a long
time. In order to exploit their full potential, enzymes often need to be re-engineered or …

The two main strategies for enzyme engineering, directed evolution and rational design,
have found widespread applications in improving the intrinsic activities of proteins. Although …

The field of artificial metalloenzymes (ArMs) is rapidly growing and ArMs are attracting
increasing attention, for example, in the fields of biosensing and drug therapy. Protein …

Artificial enzymes, which are hybrids of proteins with abiological catalytic groups, have
emerged as a powerful approach towards the creation of enzymes for new-to-nature …

Considering the intrinsic toxicities of transition metals, their incorporation into drug therapies
must operate at minimal amounts while ensuring adequate catalytic activity within complex …

Conspectus The biotechnological revolution has made it possible to create enzymes for
many reactions by directed evolution. However, because of the immense number of …

Chirality, an inherent characteristic observed throughout nature, plays a pivotal role across a
wide range of scales, from subatomic to galactic, and holds significance in myriad scientific …

Devising artificial photoenzymes for abiological bond-forming reactions is of high synthetic
value but also a tremendous challenge. Disclosed herein is the first photobiocatalytic cross …