Techniques for the detection of sickle cell disease: a review

WA Arishi, HA Alhadrami, M Zourob - Micromachines, 2021 - mdpi.com
Sickle cell disease (SCD) is a widespread disease caused by a mutation in the beta-globin
gene that leads to the production of abnormal hemoglobin called hemoglobin S. The …

From the bench to the field in low‐cost diagnostics: two case studies

AA Kumar, JW Hennek, BS Smith… - Angewandte Chemie …, 2015 - Wiley Online Library
Despite the growth of research in universities on point‐of‐care (POC) diagnostics for global
health, most devices never leave the laboratory. The processes that move diagnostic …

Magnetic levitation in chemistry, materials science, and biochemistry

S Ge, A Nemiroski, KA Mirica, CR Mace… - Angewandte Chemie …, 2020 - Wiley Online Library
All matter has density. The recorded uses of density to characterize matter date back to as
early as ca. 250 BC, when Archimedes was believed to have solved “The Puzzle of The …

Translating diagnostics and drug delivery technologies to low-resource settings

EM Euliano, AA Sklavounos, AR Wheeler… - Science translational …, 2022 - science.org
Diagnostics and drug delivery technologies engineered for low-resource settings aim to
meet their technical design specifications using strategies that are compatible with limited …

Magnetic levitation systems for disease diagnostics

AA Ashkarran, M Mahmoudi - Trends in Biotechnology, 2021 - cell.com
Magnetic levitation (MagLev) is a well-documented, robust technique for density
measurements and separations. Although the potential of MagLev as an emerging tool in …

The pressing need for point-of-care diagnostics for sickle cell disease: A review of current and future technologies

PT McGann, C Hoppe - Blood Cells, Molecules, and Diseases, 2017 - Elsevier
Sickle cell disease (SCD) is a common and life threatening inherited blood disorder,
affecting over 300,000 newborns per year. Over 75% of SCD births occur in sub-Saharan …

[HTML][HTML] White paper: pathways to progress in newborn screening for sickle cell disease in sub-Saharan Africa

L Hsu, OE Nnodu, BJ Brown, F Tluway… - Journal of tropical …, 2018 - ncbi.nlm.nih.gov
Abstract Sickle Cell Disease (SCD) is among the most common single-gene diseases in the
world but evidence-based comprehensive health care has not been implemented where the …

Point-of-care microchip electrophoresis for integrated anemia and hemoglobin variant testing

R An, Y Man, S Iram, E Kucukal, MN Hasan, Y Huang… - Lab on a Chip, 2021 - pubs.rsc.org
Anemia affects over 25% of the world's population with the heaviest burden borne by women
and children. Genetic hemoglobin (Hb) variants, such as sickle cell disease, are among the …

Characteristics of a rapid, point‐of‐care lateral flow immunoassay for the diagnosis of sickle cell disease

PT McGann, BA Schaefer, M Paniagua… - American journal of …, 2016 - Wiley Online Library
Sickle cell disease (SCD) is a common and life‐threatening hematological disorder,
affecting approximately 400,000 newborns annually worldwide. Most SCD births occur in …

High-sensitivity measurement of density by magnetic levitation

A Nemiroski, AA Kumar, S Soh, DV Harburg… - Analytical …, 2016 - ACS Publications
This paper presents methods that use Magnetic Levitation (MagLev) to measure very small
differences in density of solid diamagnetic objects suspended in a paramagnetic medium …