Biowaiver monograph for immediate-release solid oral dosage forms: carbamazepine

MA García, R Cristofoletti, B Abrahamsson… - Journal of …, 2021 - Elsevier
Literature relevant to assessing whether BCS-based biowaivers can be applied to
immediate release (IR) solid oral dosage forms containing carbamazepine as the single …

Development of an advanced intestinal in vitro triple culture permeability model to study transport of nanoparticles

C Schimpel, B Teubl, M Absenger, C Meindl… - Molecular …, 2014 - ACS Publications
Intestinal epithelial cell culture models, such as Caco-2 cells, are commonly used to assess
absorption of drug molecules and transcytosis of nanoparticles across the intestinal mucosa …

A fast and validated HPLC method for simultaneous determination of dopamine, dobutamine, phentolamine, furosemide, and aminophylline in infusion samples and …

F Chen, B Fang, S Wang - Journal of Analytical Methods in …, 2021 - Wiley Online Library
A simple, fast, and validated HPLC method was developed for the simultaneous
quantization of five cardiovascular agents: dopamine (DPM), dobutamine (DBM) …

Phenytoin carried by silica core iron oxide nanoparticles reduces the expression of pharmacoresistant seizures in rats

A Rosillo-de la Torre, L Zurita-Olvera… - …, 2015 - Taylor & Francis
Aim: The present study was focused to evaluate the anticonvulsant effects of phenytoin
(PHT) loaded in the silica core of iron oxide nanoparticles (NPs) in an animal model with …

Colorimetric approach based on iron oxide magnetic molecularly imprinted nanozyme for sensitive determination of antipyrine and benzocaine: Application to …

AM Hassan, KM Kelani, MA Hegazy, AH Nadim - Microchemical Journal, 2024 - Elsevier
Nanozymes provide the required enzymatic activity however, they lack the selectivity to
target a certain drug during analysis. Herein, a novel polydopamine molecularly imprinted …

Development of a novel in vitro 3D intestinal model for permeability evaluations

J Zhang, J Penny, JR Lu - … Journal of Food Sciences and Nutrition, 2020 - Taylor & Francis
In this work, a new three-dimensional (3D) in vitro cell model was described, which was
comprised of an epithelium, a subepithelial fibroblast network and an extracellular matrix …

Assessment of biopharmaceutical performance of supersaturating formulations of carbamazepine in rats using physiologically based pharmacokinetic modeling

SD Thakore, PS Thakur, G Shete, R Gangwal… - AAPS …, 2019 - Springer
There is an overgrowing emphasis on supersaturating drug delivery systems (SDDS) with
increase in number of poorly water-soluble compounds. However, biopharmaceutical …

Therapeutic drug monitoring and methods of quantitation for carbamazepine

C Tuchila, DL Baconi, C Dinu Pirvu… - Journal of Mind and …, 2017 - scholar.valpo.edu
Carbamazepine is an early anticonvulsant still used today in the treatment of several forms
of epilepsy. An active metabolite in the human body contributes to its pharmacological effect …

Quantification of carbamazepine and its 10, 11‐epoxide metabolite in rat plasma by UPLC‐UV and application to pharmacokinetic study

A Beig, A Dahan - Biomedical Chromatography, 2014 - Wiley Online Library
ABSTRACT A rapid, selective and sensitive UPLC‐UV method was developed and
validated for the quantitative analysis of carbamazepine and its epoxide metabolite in rat …

Degradation of antipyrine in the Fenton-like process with a La-doped heterogeneous catalyst

S Wei, C Zeng, Y Lu, G Liu, H Luo, R Zhang - Frontiers of Environmental …, 2019 - Springer
The aim of this study was to synthesize a novel lanthanum (La) doped catalyst and to
investigate antipyrine removal in wastewater using the Fenton-like process with the catalyst …