Ursolic acid—a pentacyclic triterpenoid with a wide spectrum of pharmacological activities

Ł Woźniak, S Skąpska, K Marszałek - Molecules, 2015 - mdpi.com
Ursolic acid (UA) is a natural terpene compound exhibiting many pharmaceutical properties.
In this review the current state of knowledge about the health-promoting properties of this …

Herbal medicine: biomolecular and clinical aspects

IFF Benzie, S Wachtel-Galor - 2011 - books.google.com
Responding to the increased popularity of herbal medicines and other forms of
complementary or alternative medicine world-wide, this reference reviews and evaluates …

Ursolic acid inhibits nuclear factor-κB activation induced by carcinogenic agents through suppression of IκBα kinase and p65 phosphorylation: correlation with down …

S Shishodia, S Majumdar, S Banerjee, BB Aggarwal - Cancer research, 2003 - AACR
The process of tumorigenesis requires cellular transformation, hyperproliferation, invasion,
angiogenesis, and metastasis. Several genes that mediate these processes are regulated …

Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the membrane-anchored glycoprotein RECK

C Takahashi, Z Sheng, TP Horan… - Proceedings of the …, 1998 - National Acad Sciences
A human fibroblast cDNA expression library was screened for cDNA clones giving rise to flat
colonies when transfected into v-Ki-ras-transformed NIH 3T3 cells. One such gene, RECK …

Phytochemicals of cranberries and cranberry products: characterization, potential health effects, and processing stability

E Pappas, KM Schaich - Critical reviews in food science and …, 2009 - Taylor & Francis
Emerging evidence is elucidating how non-nutrient phytochemicals underlie the health
promotion afforded by fruits and vegetables. This review focuses on Vaccinium …

Potent anti-inflammatory activity of ursolic acid, a triterpenoid antioxidant, is mediated through suppression of NF-κB, AP-1 and NF-AT

R Checker, SK Sandur, D Sharma, RS Patwardhan… - PloS one, 2012 - journals.plos.org
Background Ursolic acid (UA), a pentacyclic triterpenoid carboxylic acid, is the major
component of many plants including apples, basil, cranberries, peppermint, rosemary …

Anti-inflammatory activity of ursolic acid in MPTP-induced parkinsonian mouse model

SN Rai, W Zahra, SS Singh, H Birla, C Keswani… - Neurotoxicity …, 2019 - Springer
Neuroinflammation plays an important role in the progression of Parkinson's disease (PD)
and hence may represent a target for treatment. The drugs used currently for PD only …

Potential of spice-derived phytochemicals for cancer prevention

BB Aggarwal, AB Kunnumakkara, KB Harikumar… - Planta …, 2008 - thieme-connect.com
Although spices have been used for thousands of years and are known for their flavor, taste
and color in the food, they are not usually recognized for their medicinal value. Extensive …

[HTML][HTML] Cranberry and its phytochemicals: a review of in vitro anticancer studies

CC Neto - The Journal of nutrition, 2007 - Elsevier
This article reviews the existing research on the anticancer properties of cranberry fruit and
key phytochemicals that are likely contributors to chemoprevention. Results from in vitro …

Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis‐associated properties in A431 cells overexpressing epidermal growth …

YT Huang, JJ Hwang, PP Lee, FC Ke… - British journal of …, 1999 - Wiley Online Library
Flavonoids display a wide range of pharmacological properties including anti‐inflammatory.
Anti‐mutagenic, anti‐carcinogenic and anti‐cancer effects. Here, we evaluated the effects of …