Marine specialized metabolites (MSM) represent a fascinating realm of chemical diversity
with multifaceted functions across the spectrum of life on Earth. These metabolites serve as …

Actinomycete bacteria derived from marine environments are a good source of natural
products with diverse biological activities such as cytotoxicity, antiviral, and antimicrobial …

We present the newly isolated Streptomyces sungeiensis SD3 strain as a promising
microbial chassis for heterologous production of secondary metabolites. S. sungeiensis SD3 …

Natural products have long served as critical raw materials in chemical and pharmaceutical
manufacturing, primarily which can provide superior scaffolds or intermediates for drug …

As a treasure trove of natural products (NPs), various fungal species possess great potential
as cell factories for valuable NPs bioproduction. However, they have many silent …

Marine symbiotic and epiphyte microorganisms are sources of bioactive or structurally novel
natural products. Metabolic blockade-based genome mining has been proven to be an …

Streptomyces offer a wealth of naturally occurring compounds with diverse structures, many
of which possess significant pharmaceutical values. However, new product exploration and …

The marine bacterium Streptomyces sp. HNS054 shows promise as a platform for producing
natural products. Isolated from a marine sponge, HNS054 possesses several desirable traits …

Liquid chromatography-mass spectrometry (LC-MS/MS)-based molecular networking
analysis was applied to Streptomyces sp. MC16. The automatic classification of the …

Microbial natural products are secondary metabolites synthesized by enzymes encoded by
biosynthetic gene clusters (BGCs). A large portion of these BGCs remains dormant or silent …