Comparative studies of gene expression and the evolution of gene regulation

IG Romero, I Ruvinsky, Y Gilad - Nature Reviews Genetics, 2012 - nature.com
The hypothesis that differences in gene regulation have an important role in speciation and
adaptation is more than 40 years old. With the advent of new sequencing technologies, we …

Gene regulation and speciation

KL Mack, MW Nachman - Trends in Genetics, 2017 - cell.com
Understanding the genetic architecture of speciation is a major goal in evolutionary biology.
Hybrid dysfunction is thought to arise most commonly through negative interactions between …

A deficit of detoxification enzymes: pesticide sensitivity and environmental response in the honeybee

C Claudianos, H Ranson, RM Johnson… - Insect molecular …, 2006 - Wiley Online Library
The honeybee genome has substantially fewer protein coding genes (≈ 11 000 genes) than
Drosophila melanogaster (≈ 13 500) and Anopheles gambiae (≈ 14 000). Some of the …

Detecting signatures of selection on gene expression

PD Price, DH Palmer Droguett, JA Taylor… - Nature Ecology & …, 2022 - nature.com
A substantial amount of phenotypic diversity results from changes in gene expression levels
and patterns. Understanding how the transcriptome evolves is therefore a key priority in …

Gene expression divergence recapitulates the developmental hourglass model

AT Kalinka, KM Varga, DT Gerrard, S Preibisch… - Nature, 2010 - nature.com
The observation that animal morphology tends to be conserved during the embryonic
phylotypic period (a period of maximal similarity between the species within each animal …

Neutral and adaptive variation in gene expression

A Whitehead, DL Crawford - Proceedings of the National …, 2006 - National Acad Sciences
Variation among populations in gene expression should be related to the accumulation of
random-neutral changes and evolution by natural selection. The following evolutionary …

Sex-specific and lineage-specific alternative splicing in primates

R Blekhman, JC Marioni, P Zumbo… - Genome …, 2010 - genome.cshlp.org
Comparative studies of gene regulation suggest an important role for natural selection in
shaping gene expression patterns within and between species. Most of these studies …

Fundulus as the premier teleost model in environmental biology: opportunities for new insights using genomics

KG Burnett, LJ Bain, WS Baldwin, GV Callard… - … and Physiology Part D …, 2007 - Elsevier
A strong foundation of basic and applied research documents that the estuarine fish
Fundulus heteroclitus and related species are unique laboratory and field models for …

Variation within and among species in gene expression: raw material for evolution

A Whitehead, DL Crawford - Molecular ecology, 2006 - Wiley Online Library
Heritable variation in regulatory or coding regions is the raw material for evolutionary
processes. The advent of microarrays has recently promoted examination of the extent of …

Evolution of primate gene expression

P Khaitovich, W Enard, M Lachmann… - Nature Reviews …, 2006 - nature.com
It has been suggested that evolutionary changes in gene expression account for most
phenotypic differences between species, in particular between humans and apes. What …