An animal model to study human infectious diseases should accurately reproduce the
various aspects of disease. Domestic pigs (Sus scrofa domesticus) are closely related to …

Influenza virus infections pose a significant threat to public health due to annual seasonal
epidemics and occasional pandemics. Influenza is also associated with significant economic …

Background Mesenchymal stem (stromal) cells (MSCs) mediate their immunoregulatory and
tissue repair functions by secreting paracrine factors, including extracellular vesicles (EVs) …

Background The underlying changes of peripheral blood inflammatory cells (PBICs) in
COVID-19 patients are little known. Moreover, the risk factors for the underlying changes of …

Since 2013, there have been several alarming influenza‐related events; the spread of highly
pathogenic avian influenza H5 viruses into North America, the detection of H10N8 and …

Influenza A virus in swine (IAV-S) is one of the most important infectious disease agents of
swine in North America. In addition to the economic burden of IAV-S to the swine industry …

Swine influenza virus (SwIV) is one of the important zoonotic pathogens. Current flu
vaccines have failed to provide cross-protection against evolving viruses in the field. Poly …

Gnotobiotic (GN) rodent models have provided insight into the contributions of the gut
microbiota to host health and preventing disease. However, rodent models are limited by …

Influenza A viruses (IAVs) infect a variety of hosts, including humans, swine, and various
avian species. The annual influenza disease burden in the human population remains …

Commercial vaccines currently available against swine influenza virus (SIV) are inactivated,
adjuvanted, whole virus vaccines, based on H1N1 and/or H3N2 and/or H1N2 SIVs. In …