[HTML][HTML] Recent research on Gulf War illness and other health problems in veterans of the 1991 Gulf War: Effects of toxicant exposures during deployment

RF White, L Steele, JP O'Callaghan, K Sullivan… - Cortex, 2016 - Elsevier
Abstract Veterans of Operation Desert Storm/Desert Shield− the 1991 Gulf War (GW)− are a
unique population who returned from theater with multiple health complaints and disorders …

Impact of endocrine-disrupting chemicals on neural development and the onset of neurological disorders

M Kajta, AK Wójtowicz - Pharmacological Reports, 2013 - Springer
Even though high doses of organic pollutants are toxic, relatively low concentrations have
been reported to cause long-term alterations in functioning of individual organisms …

Melatonin improves brain function in a model of chronic Gulf War Illness with modulation of oxidative stress, NLRP3 inflammasomes, and BDNF-ERK-CREB pathway …

LN Madhu, M Kodali, S Attaluri, B Shuai, L Melissari… - Redox Biology, 2021 - Elsevier
Persistent cognitive and mood dysfunction is the primary CNS symptom in veterans afflicted
with Gulf War Illness (GWI). This study investigated the efficacy of melatonin (MEL) for …

Toxicity of polystyrene nanoplastics and zinc oxide to mice

FN Estrela, ATB Guimarães, AP da Costa Araújo… - Chemosphere, 2021 - Elsevier
The toxicity of zinc oxide (ZnO NPs) and polystyrene nanoplastics (PS NaPs) has been
tested in different animal models; however, knowledge about their impact on mice remains …

In-vivo imaging of neuroinflammation in veterans with Gulf War illness

Z Alshelh, DS Albrecht, C Bergan, O Akeju… - Brain, behavior, and …, 2020 - Elsevier
Abstract Gulf War Illness (GWI) is a chronic disorder affecting approximately 30% of the
veterans who served in the 1991 Gulf War. It is characterised by a constellation of symptoms …

Altered gut microbiome in a mouse model of Gulf War Illness causes neuroinflammation and intestinal injury via leaky gut and TLR4 activation

F Alhasson, S Das, R Seth, D Dattaroy… - PloS one, 2017 - journals.plos.org
Many of the symptoms of Gulf War Illness (GWI) that include neurological abnormalities,
neuroinflammation, chronic fatigue and gastrointestinal disturbances have been traced to …

Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature and reduced glial activation

M Kodali, VK Parihar, B Hattiangady, V Mishra… - Scientific reports, 2015 - nature.com
Greatly waned neurogenesis, diminished microvasculature, astrocyte hypertrophy and
activated microglia are among the most conspicuous structural changes in the aged …

Corticosterone primes the neuroinflammatory response to DFP in mice: potential animal model of Gulf War Illness

JP O'Callaghan, KA Kelly, AR Locker… - Journal of …, 2015 - Wiley Online Library
Abstract Gulf War Illness (GWI) is a multi‐symptom disorder with features characteristic of
persistent sickness behavior. Among conditions encountered in the Gulf War (GW) theater …

Neuroinflammation in Gulf War Illness is linked with HMGB1 and complement activation, which can be discerned from brain-derived extracellular vesicles in the blood

LN Madhu, S Attaluri, M Kodali, B Shuai… - Brain, behavior, and …, 2019 - Elsevier
Cognitive dysfunction and neuroinflammation are conspicuously observed in Gulf War
Illness (GWI). We investigated whether brain inflammation in GWI is associated with …

Gulf War illness: mechanisms underlying brain dysfunction and promising therapeutic strategies

B Dickey, LN Madhu, AK Shetty - Pharmacology & therapeutics, 2021 - Elsevier
Abstract Gulf War Illness (GWI), a chronic multisymptom health problem, afflicts~ 30% of
veterans served in the first GW. Impaired brain function is among the most significant …