Background External evidence is commonly used to inform survival modeling for health
technology assessment (HTA). While there are a range of methodological approaches that …

Background/purpose Curative technologies improve patient's survival and/or quality of life
but increase financial burdens. Effective prevention benefits all three. We summarize …

Background: The absolute burden of stroke in Korea is ever growing. Many studies have
explored the outcomes of mortality, quality of life (QOL), and/or economic burden with limited …

To quantify the societal impact of disability in patients with non-small cell lung cancer
(NSCLC), this study estimated the disability-free life expectancy (DFLE), loss-of-DFLE and …

Background In health technology assessment, restricted mean survival time and life
expectancy are commonly evaluated. Parametric models are typically used for extrapolation …

Background Health policy decisions are often informed by estimates of long-term survival
based primarily on short-term data. A range of methods are available to include longer-term …

Objective Studies that examine the broad allocation of resources, regardless of who bears
the costs, should ideally estimate costs from a societal perspective. We have successfully …

Background Survival heterogeneity and limited trial follow-up present challenges for
estimating lifetime benefits of oncology therapies. This study used CheckMate 067 …

Introduction Clinical trials often have short follow-ups, and long-term outcomes such as
survival must be extrapolated. Current extrapolation methods often produce a wide range of …

Non-healing wounds are a serious complication in diabetic patients. One of the detrimental
factors contributing to limited wound healing is the accumulation of metalloproteinase-9 …