Autophagy is a powerful tool that host cells use to defend against viral infection. Double-
membrane vesicles, termed autophagosomes, deliver trapped viral cargo to the lysosome …

Lipids are essential building blocks synthesized by complex molecular pathways and
deposited as lipid droplets (LDs) in cells. LDs are evolutionary conserved organelles found …

Deregulation of autophagy is proposed to play a key pathogenic role in hepatocellular
carcinoma (HCC), the most common primary malignancy of the liver and the third leading …

Objective Autophagy is an intracellular degradation pathway conserved in all eukaryotes
from yeast to humans. This process plays a quality‐control role by destroying harmful …

Photodynamic therapy (PDT) has shown great potential for overcoming drug-resistant
cancers. Here, we report a multifunctional drug delivery system based on chlorin e6 …

Autophagy is an evolutionarily conserved lysosomal-dependent pathway for degrading
cytoplasmic proteins, macromolecules, and organelles. Autophagy-related genes (Atgs) are …

Despite great scientific breakthroughs toward understanding the identity of human
hepatocellular carcinoma (HCC) mechanistically, there are still no clinically efficient …

Nonalcoholic fatty liver disease (NAFLD) is becoming an increasingly serious disease
worldwide. Unfortunately, no specific drug has been approved to treat NAFLD. Accumulating …

Chloroquines are 4‐aminoquinoline‐based drugs mainly used to treat malaria. At
pharmacological concentrations, they have significant effects on tissue homeostasis …

Understanding of the mechanism for myeloid differentiation provides important insights into
the hematopoietic developmental processes. By using an ESC-derived myeloid progenitor …