Phyto‐therapeutic potential of Withania somnifera: Molecular mechanism and health implications

N Yadav, S Tripathi, NS Sangwan - Phytotherapy Research, 2024 - Wiley Online Library
Withania somnifera, the plant named Indian ginseng, Ashwagandha, or winter cherry, has
been used since ancient times to cure various health ailments. Withania somnifera is rich in …

Amelioration of cadmium stress in Withania somnifera by ROS management: active participation of primary and secondary metabolism

B Mishra, N Singh Sangwan - Plant Growth Regulation, 2019 - Springer
Cadmium (Cd) is considered as a non-essential heavy metal with substantial toxicity on
environment. Withania somnifera, a reputed therapeutic herb exhibits vast pharmacological …

An update on biotechnological intervention mediated by plant tissue culture to boost secondary metabolite production in medicinal and aromatic plants

SP Prashant, M Bhawana - Physiologia Plantarum, 2024 - Wiley Online Library
Since prehistoric times, medicinal and aromatic plants (MAPs) have been employed for
various therapeutic purposes due to their varied array of pharmaceutically relevant bioactive …

ROS management is mediated by ascorbate-glutathione-α-tocopherol triad in co-ordination with secondary metabolic pathway under cadmium stress in Withania …

B Mishra, S Chand, NS Sangwan - Plant Physiology and Biochemistry, 2019 - Elsevier
Being static, plants are frequently exposed to various essential and non-essential heavy
metals from the surroundings. This exposure results in considerable ROS generation …

Cloning and homologous characterization of geranylgeranyl pyrophosphate synthase (GGPPS) from Withania somnifera revealed alterations in metabolic flux …

Y Srivastava, S Tripathi, B Mishra, NS Sangwan - Planta, 2022 - Springer
Main conclusion Overexpression of a novel geranylgeranyl pyrophosphate synthase gene
(WsGGPPS) in planta resulted in increased levels of gibberellic acid and decrease in …

Berry transcriptome: insights into a novel resource to understand development dependent secondary metabolism in Withania somnifera (Ashwagandha)

S Tripathi, RS Sangwan, B Mishra… - Physiologia …, 2020 - Wiley Online Library
Withania somnifera (Ashwagandha) is considered as Rasayana in Indian systems of
medicine. This study reports a novel transcriptome of W. somnifera berries, with high depth …

Comparative investigation of therapeutic plant Withania somnifera for yield, productivity, withanolide content, and expression of pathway genes during contrasting …

B Mishra, SK Bose, NS Sangwan - Industrial crops and products, 2020 - Elsevier
Several environmental factors such as weather, season, temperature, biotic, and abiotic
factors affect the plant productivity and content of secondary metabolites. Present work is …

Differential regulation of key triterpene synthase gene under abiotic stress in Withania somnifera L. Dunal and its co-relation to sterols and withanolides

B Mishra, S Bansal, S Tripathi, S Mishra… - Plant Physiology and …, 2024 - Elsevier
Withania somnifera (Ashwagandha), is one of the most reputed Indian medicinal plants,
having immense pharmacological activities due to the occurrence of withanolides. The …

Novel archetype in cancer therapeutics: exploring prospective of phytonanocarriers

N Yadav, D Singh, M Rawat, N Sangwan - 3 Biotech, 2022 - Springer
This paper reports various types of cancer, their incidence, and prevalence all over the
globe. Along with the discovery of novel natural drugs for cancer treatment, these present a …

Traditional Indian knowledge of immunity from plants

NS Chauhan, MR Singh, V Sharma, N Yadav… - … and Phytomolecules for …, 2022 - Springer
The traditional Indian medicine like Ayurveda and Siddha and traditional Chinese medicine
remain the most ancient therapies. While Ayurveda originated in North and is popular in …