It is from the discovery of leptin and the central nervous system as a regulator of bone
remodeling that the presence of autonomic nerves within the skeleton transitioned from a …

The skeleton is no longer seen as a static, isolated, and mostly structural organ. Over the last
two decades, a more complete picture of the multiple functions of the skeleton has emerged …

A differentiation switch of bone marrow mesenchymal stem/stromal cells (BMSCs) from
osteoblasts to adipocytes contributes to age‐and menopause‐associated bone loss and …

Context Although blood pressure variability (BPV) is associated with various health
outcomes, only 1 study suggested that BPV is correlated with hip fractures. As …

Efficient regeneration of bone defects caused by disease or significant trauma is a major
challenge in current medicine, which is particularly difficult yet significant under the …

Bone marrow adipose tissue (BMAT) is an important cellular component of the skeleton.
Understanding how it is regulated by the nervous system is crucial to the study of bone and …

Among 1299 older adults with 24-h Holter monitoring data at baseline, followed for
approximately 15 years, 190 incident hip fractures occurred. Increased heart rate variability …

Increased β-adrenergic receptor activity has been hypothesized to cause bone loss in those
with dementia. We investigated the effect of long-term β-blocker use on rate of bone loss in …

Introduction A higher incidence of neural dysfunction in people with obesity has been
described. We determined the prevalence of neuropathic lesions in obese women and …

Purpose Genetic knockout or pharmacological inhibition of the beta-2 adrenergic receptor
(B2AR) increased bone mass, whereas stimulation decreased bone mass in rodents. In …