Update οn the diagnosis and management of systemic lupus erythematosus

A Fanouriakis, N Tziolos, G Bertsias… - Annals of the rheumatic …, 2021 - ard.bmj.com
Clinical heterogeneity, unpredictable course and flares are characteristics of systemic lupus
erythematosus (SLE). Although SLE is—by and large—a systemic disease, occasionally it …

EULAR recommendations for the management of systemic lupus erythematosus: 2023 update

A Fanouriakis, M Kostopoulou, J Andersen… - Annals of the …, 2024 - ard.bmj.com
Objectives To update the EULAR recommendations for the management of systemic lupus
erythematosus (SLE) based on emerging new evidence. Methods An international Task …

Safety and efficacy of long‐term Voclosporin treatment for lupus nephritis in the phase 3 AURORA 2 clinical trial

A Saxena, EM Ginzler, K Gibson… - Arthritis & …, 2024 - Wiley Online Library
Objective AURORA 2 evaluated the long‐term safety, tolerability, and efficacy of voclosporin
compared to placebo in patients with lupus nephritis (LN) receiving an additional two years …

Flares in lupus nephritis: risk factors and strategies for their prevention

A Banos, G Bertsias - Current Rheumatology Reports, 2023 - Springer
Abstract Purpose of Review Discuss the prognostic significance of kidney flares in patients
with lupus nephritis, associated risk factors, and possible preventative strategies. Recent …

[HTML][HTML] Mortality and causes of death in systemic lupus erythematosus over the last decade: Data from a large population-based study

M Zen, L Salmaso, CB Amidei, U Fedeli, S Bellio… - European Journal of …, 2023 - Elsevier
Objective To assess mortality rates (MRs), standardized mortality ratios, and causes of death
in systemic lupus erythematosus (SLE) in a population-based study. Methods We analyzed …

Durable renal response and safety with add-on belimumab in patients with lupus nephritis in real-life setting (BeRLiSS-LN). Results from a large, nationwide …

M Gatto, F Saccon, L Andreoli, E Bartoloni… - Journal of …, 2021 - Elsevier
Background Belimumab was recently approved for treatment of lupus glomerulonephritis
(LN). Aim To evaluate renal response and its predictors in LN patients receiving belimumab …

[HTML][HTML] When should targeted therapies be used in the treatment of lupus nephritis: Early in the disease course or in refractory patients?

I Parodis, R Depascale, A Doria, HJ Anders - Autoimmunity Reviews, 2024 - Elsevier
Although the prognosis of lupus nephritis (LN) has improved over the last few decades, 5–
20% of patients still progress to kidney failure. Hence, there is an unmet need to improve the …

Proteinuria and hematuria after remission induction are associated with outcome in ANCA-associated vasculitis

N Benichou, P Charles, B Terrier, RB Jones… - Kidney International, 2023 - Elsevier
In anti-neutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV), hematuria and
proteinuria are biomarkers reflecting kidney involvement at diagnosis. Yet, the prognostic …

One year in review 2021: systemic lupus erythematosus

F Trentin, D Zucchi, V Signorini, E Elefante… - Clinical and …, 2021 - sfera.unife.it
In 2020 many contributions have been produced on SLE. Our critical digest of the recent
literature will be focused on genetic factors that contribute to the development of the disease …

Immunosuppressive therapy withdrawal after remission achievement in patients with lupus nephritis

M Zen, E Fuzzi, M Loredo Martinez, R Depascale… - …, 2022 - academic.oup.com
Objectives Whether immunosuppressive therapy may be safely withdrawn in lupus nephritis
(LN) is still unclear. We assessed rate and predictors of flare after IS withdrawal in patients …